Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation: Spatially variable opportunities for outcrossing in an obligate pathogen

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Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation : Spatially variable opportunities for outcrossing in an obligate pathogen. / Laine, Anna Liisa; Barrès, Benoit; Numminen, Elina; Sirén, Jukka P.

julkaisussa: ELIFE, Vuosikerta 8, 01.06.2019.

Tutkimustuotos: Lehtiartikkelivertaisarvioitu

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@article{435290eeee0c42b18a991bcf368952b3,
title = "Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation: Spatially variable opportunities for outcrossing in an obligate pathogen",
abstract = "Many pathogens possess the capacity for sex through outcrossing, despite being able to reproduce also asexually and/or via selfing. Given that sex is assumed to come at a cost, these mixed reproductive strategies typical of pathogens have remained puzzling. While the ecological and evolutionary benefits of outcrossing are theoretically well-supported, support for such benefits in pathogen populations are still scarce. Here, we analyze the epidemiology and genetic structure of natural populations of an obligate fungal pathogen, Podosphaera plantaginis. We find that the opportunities for outcrossing vary spatially. Populations supporting high levels of coinfection –a prerequisite of sex – result in hotspots of novel genetic diversity. Pathogen populations supporting coinfection also have a higher probability of surviving winter. Jointly our results show that outcrossing has direct epidemiological consequences as well as a major impact on pathogen population genetic diversity, thereby providing evidence of ecological and evolutionary benefits of outcrossing in pathogens.",
keywords = "Cost of sex, Diversity, Epidemiology, Outcrossing, Overwintering",
author = "Laine, {Anna Liisa} and Benoit Barr{\`e}s and Elina Numminen and Sir{\'e}n, {Jukka P.}",
note = "| openaire: EC/H2020/281517/EU//PATHEVOL | openaire: EC/H2020/724508/EU//RESISTANCE",
year = "2019",
month = "6",
day = "1",
doi = "10.7554/eLife.47091.001",
language = "English",
volume = "8",
journal = "ELIFE",
issn = "2050-084X",
publisher = "ELIFE SCIENCES PUBLICATIONS LTD",

}

RIS - Lataa

TY - JOUR

T1 - Variable opportunities for outcrossing result in hotspots of novel genetic variation in a pathogen metapopulation

T2 - Spatially variable opportunities for outcrossing in an obligate pathogen

AU - Laine, Anna Liisa

AU - Barrès, Benoit

AU - Numminen, Elina

AU - Sirén, Jukka P.

N1 - | openaire: EC/H2020/281517/EU//PATHEVOL | openaire: EC/H2020/724508/EU//RESISTANCE

PY - 2019/6/1

Y1 - 2019/6/1

N2 - Many pathogens possess the capacity for sex through outcrossing, despite being able to reproduce also asexually and/or via selfing. Given that sex is assumed to come at a cost, these mixed reproductive strategies typical of pathogens have remained puzzling. While the ecological and evolutionary benefits of outcrossing are theoretically well-supported, support for such benefits in pathogen populations are still scarce. Here, we analyze the epidemiology and genetic structure of natural populations of an obligate fungal pathogen, Podosphaera plantaginis. We find that the opportunities for outcrossing vary spatially. Populations supporting high levels of coinfection –a prerequisite of sex – result in hotspots of novel genetic diversity. Pathogen populations supporting coinfection also have a higher probability of surviving winter. Jointly our results show that outcrossing has direct epidemiological consequences as well as a major impact on pathogen population genetic diversity, thereby providing evidence of ecological and evolutionary benefits of outcrossing in pathogens.

AB - Many pathogens possess the capacity for sex through outcrossing, despite being able to reproduce also asexually and/or via selfing. Given that sex is assumed to come at a cost, these mixed reproductive strategies typical of pathogens have remained puzzling. While the ecological and evolutionary benefits of outcrossing are theoretically well-supported, support for such benefits in pathogen populations are still scarce. Here, we analyze the epidemiology and genetic structure of natural populations of an obligate fungal pathogen, Podosphaera plantaginis. We find that the opportunities for outcrossing vary spatially. Populations supporting high levels of coinfection –a prerequisite of sex – result in hotspots of novel genetic diversity. Pathogen populations supporting coinfection also have a higher probability of surviving winter. Jointly our results show that outcrossing has direct epidemiological consequences as well as a major impact on pathogen population genetic diversity, thereby providing evidence of ecological and evolutionary benefits of outcrossing in pathogens.

KW - Cost of sex

KW - Diversity

KW - Epidemiology

KW - Outcrossing

KW - Overwintering

UR - http://www.scopus.com/inward/record.url?scp=85071847226&partnerID=8YFLogxK

U2 - 10.7554/eLife.47091.001

DO - 10.7554/eLife.47091.001

M3 - Article

VL - 8

JO - ELIFE

JF - ELIFE

SN - 2050-084X

ER -

ID: 37052537