Understanding mechanobiology – Linking the mechanical stimulation to cellular response

F. Melo-Fonseca, Ines Mendes Pinto, Michael Gasik, Filipe Samuel Silva, G. Miranda

Tutkimustuotos: Artikkeli kirjassa/konferenssijulkaisussaConference article in proceedingsScientificvertaisarvioitu

142 Lataukset (Pure)

Abstrakti

Mechanical loading plays a crucial role throughout humans’ lifetime since their embryonic development up to the tissues’ homeostasis. Depending on the cell type and location, these mechanical stimuli regulate specific cell functions,
namely gene expression, cell growth, differentiation and death. Cells are highly dynamic and it still remains unclear how cells sense these forces and convert them into biochemical responses. This review aims to provide an introductory research of the load-sensitive cells’ mechanobiology present in the bone tissue. Subsequently, this study will contribute to design novel orthopedic implants that overcome their current impaired fixation to the natural bone.
AlkuperäiskieliEnglanti
OtsikkoResumos alargados do 8º Congresso Nacional de Biomecânica
Alaotsikko15 e 16 de fevereiro de 2019, Unhais da Serra, Covilhã
ToimittajatAntónio Completo, António Ramos, Aurélio Faria
JulkaisupaikkaAveiro
KustantajaUniversidade de Aveiro
Sivut189-190
Painos1
ISBN (elektroninen)978-972-789-586-1
TilaJulkaistu - 12 maalisk. 2019
OKM-julkaisutyyppiA4 Artikkeli konferenssijulkaisussa
TapahtumaCongresso Nacional de Biomecânica - Covilhã, Portugali
Kesto: 15 helmik. 201916 helmik. 2019
Konferenssinumero: 8

Conference

ConferenceCongresso Nacional de Biomecânica
Maa/AluePortugali
KaupunkiCovilhã
Ajanjakso15/02/201916/02/2019

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