Synthesis of sandwich-structured silver@polydopamine@silver shells with enhanced antibacterial activities

Tutkimustuotos: Lehtiartikkelivertaisarvioitu


  • Bin Shang
  • Miao Xu
  • Zelun Zhi
  • Yuewei Xi
  • Yanbing Wang
  • Bo Peng
  • Peng Li
  • Ziwei Deng


  • Shaanxi Normal University
  • Nanjing Tech University
  • Northwestern Polytechnical University Xian
  • Xi'an Jiaotong University


The unique antibacterial characteristics of Ag nanomaterials offer a wide potential range of applications, but achieving rapid and durable antibacterial efficacy is challenging. This is because the speed and durability of the antibacterial function make conflicting demands on the structural design: the former requires the direct exposure of Ag to the surrounding environment, whereas the durability requires Ag to be protected from the environment. To overcome this incompatibility, we synthesize sandwich-structured polydopamine shells decorated both internally and externally with Ag nanoparticles, which exhibit prompt and lasting bioactivity in applications. These shells are biocompatible and can be used in vivo to counter bacterial infection caused by methicillin-resistant Staphylococcus aureus superbugs and to inhibit biofilm formation. This work represents a new paradigm for the design of composite materials with enhanced antibacterial properties.


JulkaisuJournal of Colloid and Interface Science
TilaJulkaistu - 15 joulukuuta 2019
OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

ID: 37469453