@inproceedings{b0d50fdd502d43da99dec6b8afb1f113,
title = "Submillimeter-wave imaging assisted alignment of millimeter-wave spectroscopic system for quantification of corneal water content",
abstract = "We propose an alignment strategy for millimeter spectroscopy of cornea that uses imaging to screen for sufficient alignment conditions. The performance of different corneal imaging objectives, in the presence of misalignment, is evaluated. The cornea is illuminated with a TEM00 Gaussian beam at 650 GHz and the beam is swept across the cornea. Images are generated by calculating the coupling between illumination and scattered beams for each illumination beam position and angle. The cornea is displaced at intervals of 500 microns in the transverse and axial directions and with new coupling coefficient maps generated at each misaligned position. Contrast in the misaligned cases are compared to the aligned case via zero normalized spatial cross correlation. The results show a maximum normalized cross correlation of 0.92 for a two-mirror scanning system and 0.74 for a one-mirror scanning objective. The analysis suggests that imaging contrast at 650 GHz can be used to screen for misalignment that would be difficult to detect with MMW.",
keywords = "Cornea, medical imaging, physical optics, quasioptics, submillimeter wave remote sensing, THz, THz imaging",
author = "Mariangela Baggio and Yong Hu and Aleksi Tamminen and Irina Nefedova and Juha Ala-Laurinaho and Zachary Taylor",
year = "2020",
month = jan,
day = "1",
doi = "10.1117/12.2556309",
language = "English",
series = "Proceedings of SPIE : the International Society for Optical Engineering",
publisher = "SPIE",
editor = "Mona Jarrahi and Sascha Preu and Dmitry Turchinovich",
booktitle = "SPIE Conference Proceedings",
address = "United States",
note = "SPIE Photonics Europe : Terahertz Photonics ; Conference date: 06-04-2020 Through 10-04-2020",
}