Projekteja vuodessa
Abstrakti
Minimally invasive implantation of subdural electrodes can dramatically benefit the patients with various neurological diseases. In modern clinical practice, the implantation procedure of the electrode arrays remains traumatic for patients and increases postoperative infection risk. Here we report a design and insertion technique of thermally activated shape-memory polymer-based electrode array that can recover up to ten times length deformation. The compressed four-centimeter wide array can be easily packed into a three-millimeter diameter tube and subsequently deployed thought five-millimeter opening in a restricted space between a brain phantom and a simulated skull. The mechanical properties of the developed array are comparable to the materials traditionally employed for the purpose, and the electrical and signal recording properties are preserved after shape deformation and recovery. Additionally, the array is biocompatible and exhibits conformability to a curvy brain surface. The results demonstrate that insertion of the electrode array through a small hole into a restricted space similar to subdural cavity is possible, which may inspire future solution of minimal invasive implantation for patients suffering from epilepsy, amyotrophic lateral sclerosis or tetraplegia.
Alkuperäiskieli | Englanti |
---|---|
Artikkeli | 9425618 |
Sivut | 17282-17289 |
Sivumäärä | 8 |
Julkaisu | IEEE Sensors Journal |
Vuosikerta | 21 |
Numero | 15 |
Varhainen verkossa julkaisun päivämäärä | toukok. 2021 |
DOI - pysyväislinkit | |
Tila | Julkaistu - 1 elok. 2021 |
OKM-julkaisutyyppi | A1 Julkaistu artikkeli, soviteltu |
Sormenjälki
Sukella tutkimusaiheisiin 'Shape Memory Polymer-Based Insertable Electrode Array towards Minimally Invasive Subdural Implantation'. Ne muodostavat yhdessä ainutlaatuisen sormenjäljen.-
CONNECT: Connecting neural networks: Nervous-system-on- Chip Technology
01/12/2018 → 31/12/2023
Projekti: EU: Framework programmes funding
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CICLAW: Hiilirajapinnat elämän ja keinotekoisen maailman välissä
Peltola, E., Aarva, A. & Pande, I.
01/09/2019 → 31/12/2021
Projekti: Academy of Finland: Other research funding
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CICLAW: Hiilirajapinnat elämän ja keinotekoisen maailman välissä
01/09/2019 → 31/12/2021
Projekti: Academy of Finland: Other research funding