Prediction of major complications affecting very low birth weight infants

Tutkimustuotos: Artikkeli kirjassa/konferenssijulkaisussavertaisarvioitu

Tutkijat

Organisaatiot

  • Helsinki University Central Hospital
  • University of Helsinki

Kuvaus

Bronchopulmonary dysplasia (BPD), necrotizing enterocolitis (NEC), and retinopathy of prematurity (ROP) are severe complications affecting Very Low Birth Weight (VLBW) infants. Our findings show that data gathered in the intensive care unit during the first 24 or 72 hours of care can be used to predict whether a VLBW infant is at risk of developing BPD. Using Gaussian process classification, we achieved classification results with areas under the receiver operator characteristic curve of 0.85 (standard error (SE) 0.05) for 24h and 0.87 (SE 0.06) for 72h BPD data. This compares favourably with results achieved using the clinical standard SNAP-II and SNAPPE-II scores. Sensitivity for BPD was 0.52 (SE 0.06). Sensitivity for NEC and ROP was close to zero, suggesting that NEC and ROP can not be reliably predicted with this approach from our data set.

Yksityiskohdat

AlkuperäiskieliEnglanti
Otsikko2017 IEEE LIFE SCIENCES CONFERENCE (LSC)
TilaJulkaistu - 2017
OKM-julkaisutyyppiA4 Artikkeli konferenssijulkaisuussa
TapahtumaIEEE Life Sciences Conference - Sydney, Austraalia
Kesto: 13 joulukuuta 201715 joulukuuta 2017
Konferenssinumero: 1
http://lsc.ieee.org/2017/

Conference

ConferenceIEEE Life Sciences Conference
LyhennettäIEEE LSC
MaaAustraalia
KaupunkiSydney
Ajanjakso13/12/201715/12/2017
www-osoite

ID: 20479882