Mechanism of adsorption of actives onto microporous functionalised calcium carbonate (FCC)

Tutkimustuotos: Lehtiartikkelivertaisarvioitu

Tutkijat

  • Charlotte L. Levy
  • Graham Peter Matthews
  • Giuliano M. Laudone
  • Samuel Beckett
  • Andrew Turner
  • Joachim Schoelkopf
  • Patrick Gane

Organisaatiot

  • Omya International AG
  • University of Plymouth

Kuvaus

Microporous ‘functionalised’ calcium carbonate (FCC) has potential for use as a carrier for the controlled release of ‘actives’, by permeation and diffusion. We have investigated the nature of the FCC surface and the mechanism of adsorption of two typical actives, namely the anti-inflammatory drug aspirin and the flavour compound vanillin, from chloroform and aqueous ethanolic solutions. There is indirect evidence from the quantitative perturbation of Tóth isotherms that their adsorption is hindered by a stagnant diffusion layer of water trapped in the micro-porosity of the FCC. To complement previous studies of the surface of FCC, it was also tested with the cationic probe benzyltrimethylammonium bromide and the anionic probe sodium 2-naphthalenesulphonate. Experimental procedures were validated by comparison with adsorption onto ground calcium carbonate and high surface area talc.

Yksityiskohdat

AlkuperäiskieliEnglanti
Sivut603-612
Sivumäärä10
JulkaisuADSORPTION : JOURNAL OF THE INTERNATIONAL ADSORPTION SOCIETY
Vuosikerta23
Numero4
TilaJulkaistu - 1 toukokuuta 2017
OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

ID: 13437889