Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Emmanuelle Castagnoli; M.A.  Andersson; Raimo Mikkola; Laszlo Kredics; Tamás Marik; Jarek Kurnitski; Heidi Salonen

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Emmanuelle Castagnoli, M.A. Andersson, Raimo Mikkola, Laszlo Kredics, Tamás Marik, Jarek Kurnitski, Heidi Salonen

Rakennustekniikan laitos

University of Szeged

Tutkimustuotos: Artikkeli kirjassa/konferenssijulkaisussa › Conference contribution › Professional

Abstrakti

Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.

Alkuperäiskieli	Englanti
Otsikko	Sisäilmastoseminaari 2017, Helsinki, 15.03.2017
Toimittajat	Jorma Säteri, Mervi Ahola
Kustantaja	Sisäilmayhdistys ry
Sivut	227-232
Vuosikerta	35
ISBN (painettu)	978-952-5236-45-3
Tila	Julkaistu - 15 maalisk. 2017
OKM-julkaisutyyppi	D3 Ammatillisen konferenssin julkaisusarja
Tapahtuma	Sisäilmastoseminaari - Messukeskus, Helsinki, Suomi Kesto: 15 maalisk. 2017 → 15 maalisk. 2017 http://www.sisailmayhdistys.fi/Tapahtumat/Sisailmastoseminaarit/Sisailmastoseminaari-2017

Julkaisusarja

Nimi	SIY raportti 35
Kustantaja	Sisäilmayhdistys ry
ISSN (painettu)	1237-1866

Conference

Conference	Sisäilmastoseminaari
Maa/Alue	Suomi
Kaupunki	Helsinki
Ajanjakso	15/03/2017 → 15/03/2017
www-osoite	http://www.sisailmayhdistys.fi/Tapahtumat/Sisailmastoseminaarit/Sisailmastoseminaari-2017

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Linkki Sisäilmastoseminaarin esityksiin

Toksiinin kulkeutumistavat kosteusvaurioituneista rakenteista sisäilmaan
Castagnoli, E., Kurnitski, J., Mikkola, R., Ahmed, K., Piironen, J., Andersson, A., Taebnia, M., Alapieti, T., Järvi, K., Salonen, H. & Vornanen-Winqvist, C.
01/09/2015 → 31/08/2019
Projekti: Academy of Finland: Other research funding

Siteeraa tätä

Castagnoli, E., Andersson, M. A., Mikkola, R., Kredics, L., Marik, T., Kurnitski, J., & Salonen, H. (2017). Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production. teoksessa J. Säteri, & M. Ahola (Toimittajat), Sisäilmastoseminaari 2017, Helsinki, 15.03.2017 (Vuosikerta 35, Sivut 227-232). (SIY raportti 35). Sisäilmayhdistys ry.

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abstract = "Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.",

keywords = "Chaetomium-like",

author = "Emmanuelle Castagnoli and M.A. Andersson and Raimo Mikkola and Laszlo Kredics and Tam{\'a}s Marik and Jarek Kurnitski and Heidi Salonen",

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note = "Sis{\"a}ilmastoseminaari ; Conference date: 15-03-2017 Through 15-03-2017",

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Castagnoli, E , Andersson, MA , Mikkola, R, Kredics, L, Marik, T, Kurnitski, J & Salonen, H 2017, Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production. julkaisussa J Säteri & M Ahola (toim), Sisäilmastoseminaari 2017, Helsinki, 15.03.2017. Vuosikerta 35, SIY raportti 35, Sisäilmayhdistys ry, Sivut 227-232, Sisäilmastoseminaari, Helsinki, Suomi, 15/03/2017.

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production. / Castagnoli, Emmanuelle ; Andersson, M.A. ; Mikkola, Raimo et al.
Sisäilmastoseminaari 2017, Helsinki, 15.03.2017. toim. / Jorma Säteri; Mervi Ahola. Vuosikerta 35 Sisäilmayhdistys ry, 2017. s. 227-232 (SIY raportti 35).

Tutkimustuotos: Artikkeli kirjassa/konferenssijulkaisussa › Conference contribution › Professional

TY - GEN

T1 - Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

AU - Castagnoli, Emmanuelle

AU - Andersson, M.A.

AU - Mikkola, Raimo

AU - Kredics, Laszlo

AU - Marik, Tamás

AU - Kurnitski, Jarek

AU - Salonen, Heidi

PY - 2017/3/15

Y1 - 2017/3/15

N2 - Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.

AB - Chaetomium-like fungi growing on indoor building materials produce toxic substances. Fourteen toxigenic indoor Chaetomium-like isolates from buildings in Finland where investigated. Six Chaetomium globosum-like strains from indoor dusts were toxic with boar sperm assay and cytotoxic to porcine kidney cells (PK-15), emitted green fluorescence and produced chaetoglobosins inhibiting cellular glucose transport. OT7 and OT7b strains fromindoor dust were cytotoxic to PK-15 cells, non fluorescent and produced the extremely cytotoxic protein synthesis inhibitor, chaetomin. The six Chaetomium globosum-like strains were resistant to borax and very sensitive to the wetting agent genapol used in cleaning chemicals. This may indicate that indoor Chaetomium-like fungi occupy their own ecological niche in buildings.

KW - Chaetomium-like

UR - http://www.sisailmayhdistys.fi/Tapahtumat/Sisailmastoseminaarit/Sisailmastoseminaari-2017

M3 - Conference contribution

SN - 978-952-5236-45-3

VL - 35

T3 - SIY raportti 35

SP - 227

EP - 232

BT - Sisäilmastoseminaari 2017, Helsinki, 15.03.2017

A2 - Säteri, Jorma

A2 - Ahola, Mervi

PB - Sisäilmayhdistys ry

T2 - Sisäilmastoseminaari

Y2 - 15 March 2017 through 15 March 2017

ER -

Indoor chaetomium-like isolates: resistance to chemicals, fluorescence and mycotoxin production

Abstrakti

Julkaisusarja

Conference

OpenUrl-saatavuus

Muut tiedostot ja linkit

Sormenjälki

Projektit

Toksiinin kulkeutumistavat kosteusvaurioituneista rakenteista sisäilmaan

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