Individual Activation Patterns After the Stimulation of Different Motor Areas: A Transcranial Magnetic Stimulation–Electroencephalography Study

Tutkimustuotos: Lehtiartikkelivertaisarvioitu

Standard

Harvard

APA

Vancouver

Author

Bibtex - Lataa

@article{3c28ab3506434c2480f3615884b3ba36,
title = "Individual Activation Patterns After the Stimulation of Different Motor Areas: A Transcranial Magnetic Stimulation–Electroencephalography Study",
abstract = "The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) enables one to study effective connectivity and activation order in neuronal networks. To characterize effective connectivity originating from the primary motor cortex (M1), dorsal premotor area (PMd), and supplementary motor area (SMA). Three right-handed volunteers (two men, aged 25–30 years) participated in a navigated TMS–EEG experiment. M1, PMd, and SMA over the nondominant hemisphere were stimulated with 150 TMS pulses. Minimum-norm estimates were derived from the EEG data to estimate the spatial spreading of TMS-elicited neuronal activation on an individual level. The activation order of the cortical areas varied depending on the stimulated area. There were similarities and differences in the spatial distribution of the TMS-evoked potentials between subjects. Similarities in cortical activation patterns were seen at short poststimulus latencies and the differences at long latencies. This pilot study suggests that cortical activation patterns and the activation order of motor areas differ interindividually and depend on the stimulated motor area. It further indicates that TMS-activated effective connections or underlying structural connections vary between subjects. The spatial patterns of TMS-evoked potentials differ between subjects especially at long latencies, when probably more complex neuronal networks are active.",
keywords = "connectivity, electroencephalography, minimum-norm estimate, motor cortex, transcranial magnetic stimulation",
author = "Karita Salo and Selja Vaalto and Tuomas Mutanen and Matti Stenroos and Risto Ilmoniemi",
year = "2018",
month = "9",
day = "17",
doi = "10.1089/brain.2018.0593",
language = "English",
volume = "8",
pages = "420--428",
journal = "BRAIN CONNECTIVITY",
issn = "2158-0014",
publisher = "Mary Ann Liebert Inc.",
number = "7",

}

RIS - Lataa

TY - JOUR

T1 - Individual Activation Patterns After the Stimulation of Different Motor Areas

T2 - A Transcranial Magnetic Stimulation–Electroencephalography Study

AU - Salo, Karita

AU - Vaalto, Selja

AU - Mutanen, Tuomas

AU - Stenroos, Matti

AU - Ilmoniemi, Risto

PY - 2018/9/17

Y1 - 2018/9/17

N2 - The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) enables one to study effective connectivity and activation order in neuronal networks. To characterize effective connectivity originating from the primary motor cortex (M1), dorsal premotor area (PMd), and supplementary motor area (SMA). Three right-handed volunteers (two men, aged 25–30 years) participated in a navigated TMS–EEG experiment. M1, PMd, and SMA over the nondominant hemisphere were stimulated with 150 TMS pulses. Minimum-norm estimates were derived from the EEG data to estimate the spatial spreading of TMS-elicited neuronal activation on an individual level. The activation order of the cortical areas varied depending on the stimulated area. There were similarities and differences in the spatial distribution of the TMS-evoked potentials between subjects. Similarities in cortical activation patterns were seen at short poststimulus latencies and the differences at long latencies. This pilot study suggests that cortical activation patterns and the activation order of motor areas differ interindividually and depend on the stimulated motor area. It further indicates that TMS-activated effective connections or underlying structural connections vary between subjects. The spatial patterns of TMS-evoked potentials differ between subjects especially at long latencies, when probably more complex neuronal networks are active.

AB - The combination of transcranial magnetic stimulation (TMS) and electroencephalography (EEG) enables one to study effective connectivity and activation order in neuronal networks. To characterize effective connectivity originating from the primary motor cortex (M1), dorsal premotor area (PMd), and supplementary motor area (SMA). Three right-handed volunteers (two men, aged 25–30 years) participated in a navigated TMS–EEG experiment. M1, PMd, and SMA over the nondominant hemisphere were stimulated with 150 TMS pulses. Minimum-norm estimates were derived from the EEG data to estimate the spatial spreading of TMS-elicited neuronal activation on an individual level. The activation order of the cortical areas varied depending on the stimulated area. There were similarities and differences in the spatial distribution of the TMS-evoked potentials between subjects. Similarities in cortical activation patterns were seen at short poststimulus latencies and the differences at long latencies. This pilot study suggests that cortical activation patterns and the activation order of motor areas differ interindividually and depend on the stimulated motor area. It further indicates that TMS-activated effective connections or underlying structural connections vary between subjects. The spatial patterns of TMS-evoked potentials differ between subjects especially at long latencies, when probably more complex neuronal networks are active.

KW - connectivity

KW - electroencephalography

KW - minimum-norm estimate

KW - motor cortex

KW - transcranial magnetic stimulation

U2 - 10.1089/brain.2018.0593

DO - 10.1089/brain.2018.0593

M3 - Article

VL - 8

SP - 420

EP - 428

JO - BRAIN CONNECTIVITY

JF - BRAIN CONNECTIVITY

SN - 2158-0014

IS - 7

ER -

ID: 28055741