TY - JOUR
T1 - IFCN-endorsed practical guidelines for clinical magnetoencephalography (MEG)
AU - Hari, Riitta
AU - Baillet, Sylvain
AU - Barnes, Gareth
AU - Burgess, Richard
AU - Forss, Nina
AU - Gross, Joachim
AU - Hämäläinen, Matti
AU - Jensen, Ole
AU - Kakigi, Ryusuke
AU - Francois, Mauguiére
AU - Nakasato, Nobukatzu
AU - Puce, Aina
AU - Romani, Gian Luca
AU - Schnitzler, Alfons
AU - Taulu, Samu
PY - 2018/8
Y1 - 2018/8
N2 - Magnetoencephalography (MEG) records weak magnetic fields outside the human head and thereby provides millisecond-accurate information about neuronal currents supporting human brain function. MEG and electroencephalography (EEG) are closely related complementary methods and should be interpreted together whenever possible. This manuscript covers the basic physical and physiological principles of MEG and discusses the main aspects of state-of-the-art MEG data analysis. We provide guidelines for best practices of patient preparation, stimulus presentation, MEG data collection and analysis, as well as for MEG interpretation in routine clinical examinations. In 2017, about 200 whole-scalp MEG devices were in operation worldwide, many of them located in clinical environments. Yet, the established clinical indications for MEG examinations remain few, mainly restricted to the diagnostics of epilepsy and to preoperative functional evaluation of neurosurgical patients. We are confident that the extensive ongoing basic MEG research indicates potential for the evaluation of neurological and psychiatric syndromes, developmental disorders, and the integrity of cortical brain networks after stroke. Basic and clinical research is, thus, paving way for new clinical applications to be identified by an increasing number of practitioners of MEG.
AB - Magnetoencephalography (MEG) records weak magnetic fields outside the human head and thereby provides millisecond-accurate information about neuronal currents supporting human brain function. MEG and electroencephalography (EEG) are closely related complementary methods and should be interpreted together whenever possible. This manuscript covers the basic physical and physiological principles of MEG and discusses the main aspects of state-of-the-art MEG data analysis. We provide guidelines for best practices of patient preparation, stimulus presentation, MEG data collection and analysis, as well as for MEG interpretation in routine clinical examinations. In 2017, about 200 whole-scalp MEG devices were in operation worldwide, many of them located in clinical environments. Yet, the established clinical indications for MEG examinations remain few, mainly restricted to the diagnostics of epilepsy and to preoperative functional evaluation of neurosurgical patients. We are confident that the extensive ongoing basic MEG research indicates potential for the evaluation of neurological and psychiatric syndromes, developmental disorders, and the integrity of cortical brain networks after stroke. Basic and clinical research is, thus, paving way for new clinical applications to be identified by an increasing number of practitioners of MEG.
KW - MEG
KW - clinical
KW - Alzheimer's disease and dementia
KW - Analysis and interpretation
KW - Artifacts
KW - Brain maturation and development
KW - Clinical neurophysiology
KW - Dyslexia
KW - Electroencephalography
KW - Epilepsy
KW - Evoked and event-related responses
KW - Guidelines
KW - Hepatic encephalopathy
KW - Magnetoencephalography
KW - Neural oscillations
KW - Neuropsychiatric disorders
KW - Pain
KW - Parkinson's disease
KW - Preoperative evaluation
KW - Source modeling
KW - Spontaneous brain activity
KW - Stroke
KW - Transient and steady-state responses
KW - Traumatic brain injury
U2 - 10.1016/j.clinph.2018.03.042
DO - 10.1016/j.clinph.2018.03.042
M3 - Review Article
VL - 129
SP - 1720
EP - 1747
JO - Clinical Neurophysiology
JF - Clinical Neurophysiology
SN - 1388-2457
IS - 8
ER -