In the past decade halogen bond (XB) catalysis has gained considerable attention. Halo-triazoles are known XB donors, yet few examples detail their use as catalysts. As a continuation of our previous work the catalytic properties of substituted enantiomerically pure halo-triazolium salts were explored in the reaction between an imine and Danishefsky's diene leading to the formation of dihydropyridinone. The catalytic activity of the XB donors was highly dependent on the choice of the halogen atom and on the counterion. Also, it was found that impurities in the diene affected the rate of the reaction.
|Julkaisu||Journal of Organic Chemistry|
|DOI - pysyväislinkit|
|Tila||Julkaistu - 5 huhtik. 2019|
|OKM-julkaisutyyppi||A1 Julkaistu artikkeli, soviteltu|