Generation-Dependent Molecular Recognition Controls Self-Assembly in Supramolecular Dendron-Virus Complexes

Tutkimustuotos: Lehtiartikkelivertaisarvioitu

Tutkijat

Organisaatiot

  • Radboud University Nijmegen
  • University of Applied Sciences of Southern Switzerland
  • Università della Svizzera italiana

Kuvaus

In this work molecular dynamics simulation identifies a clear link between the dendron virus multivalent molecular recognition and the nature of the consequent self-assembly. Data demonstrate how a weak hydrophobic association is transformed in an electrostatic self assembly, orders of magnitude stronger, depending on the dendron generation used to assemble the viruses. This opens a new frontier in the engineering of hierarchical self assemblies, potentially enabling the control of the supra molecular properties by acting at the single-molecule level.

Yksityiskohdat

AlkuperäiskieliEnglanti
Sivut723-728
Sivumäärä6
JulkaisuNano Letters
Vuosikerta11
Numero2
TilaJulkaistu - 2011
OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

ID: 4721646