Enlargement of choroid plexus in complex regional pain syndrome

Guangyu Zhou, Jaakko Hotta, Maria K. Lehtinen, Nina Forss, Riitta Hari

Tutkimustuotos: LehtiartikkeliArticleScientificvertaisarvioitu

30 Sitaatiot (Scopus)
38 Lataukset (Pure)

Abstrakti

The choroid plexus, located in brain ventricles, has received surprisingly little attention in clinical neuroscience. In morphometric brain analysis, we serendipitously found a 21% increase in choroid plexus volume in 12 patients suffering from complex regional pain syndrome (CRPS) compared with age- and gender-matched healthy subjects. No enlargement was observed in a group of 8 patients suffering from chronic pain of other etiologies. Our findings suggest involvement of the choroid plexus in the pathogenesis of CRPS. Since the choroid plexus can mediate interaction between peripheral and brain inflammation, our findings pinpoint the choroid plexus as an important target for future research of central pain mechanisms.
AlkuperäiskieliEnglanti
Artikkeli14329
Sivut1-5
JulkaisuScientific Reports
Vuosikerta5
DOI - pysyväislinkit
TilaJulkaistu - 2015
OKM-julkaisutyyppiA1 Alkuperäisartikkeli tieteellisessä aikakauslehdessä

Sormenjälki

Sukella tutkimusaiheisiin 'Enlargement of choroid plexus in complex regional pain syndrome'. Ne muodostavat yhdessä ainutlaatuisen sormenjäljen.

Siteeraa tätä