# Dynamics of end-pulled polymer translocation through a nanopore

Tutkimustuotos: Lehtiartikkeli

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**Dynamics of end-pulled polymer translocation through a nanopore.** / Sarabadani, Jalal; Ghosh, Bappa; Chaudhury, Srabanti; Ala-Nissila, Tapio.

Tutkimustuotos: Lehtiartikkeli

### Harvard

*EPL*, Vuosikerta. 120, Nro 3, 38004, Sivut 1-6. https://doi.org/10.1209/0295-5075/120/38004

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*EPL*,

*120*(3), 1-6. [38004]. https://doi.org/10.1209/0295-5075/120/38004

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### Bibtex - Lataa

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### RIS - Lataa

TY - JOUR

T1 - Dynamics of end-pulled polymer translocation through a nanopore

AU - Sarabadani, Jalal

AU - Ghosh, Bappa

AU - Chaudhury, Srabanti

AU - Ala-Nissila, Tapio

PY - 2017/11/1

Y1 - 2017/11/1

N2 - We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory to include friction arising from the trans side subchain. The theory reveals a complicated scenario of multiple scaling regimes depending on the configurations of the cis and the trans side subchains. In the limit of high driving forces f such that the trans subchain is strongly stretched, the theory is in excellent agreement with molecular dynamics simulations and allows an exact analytic solution for the scaling of the translocation time τ as a function of the chain length N 0 and f. In this regime the asymptotic scaling exponents for are , and . The theory reveals significant correction-to-scaling terms arising from the cis side subchain and pore friction, which lead to a very slow approach to from below as a function of increasing N 0.

AB - We consider the translocation dynamics of a polymer chain forced through a nanopore by an external force on its head monomer on the trans side. For a proper theoretical treatment we generalize the iso-flux tension propagation (IFTP) theory to include friction arising from the trans side subchain. The theory reveals a complicated scenario of multiple scaling regimes depending on the configurations of the cis and the trans side subchains. In the limit of high driving forces f such that the trans subchain is strongly stretched, the theory is in excellent agreement with molecular dynamics simulations and allows an exact analytic solution for the scaling of the translocation time τ as a function of the chain length N 0 and f. In this regime the asymptotic scaling exponents for are , and . The theory reveals significant correction-to-scaling terms arising from the cis side subchain and pore friction, which lead to a very slow approach to from below as a function of increasing N 0.

UR - http://www.scopus.com/inward/record.url?scp=85042089534&partnerID=8YFLogxK

U2 - 10.1209/0295-5075/120/38004

DO - 10.1209/0295-5075/120/38004

M3 - Article

VL - 120

SP - 1

EP - 6

JO - EPL

JF - EPL

SN - 0295-5075

IS - 3

M1 - 38004

ER -

ID: 18372789