Differential inter-subject correlation of brain activity when kinship is a variable in moral dilemma

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Differential inter-subject correlation of brain activity when kinship is a variable in moral dilemma. / Bacha-Trams, Mareike; Glerean, Enrico; Dunbar, Robin; Lahnakoski, Juha M.; Ryyppö, Elisa; Sams, Mikko; Jääskeläinen, Iiro P.

julkaisussa: Scientific Reports, Vuosikerta 7, Nro 1, 14244, 01.12.2017, s. 1-16.

Tutkimustuotos: Lehtiartikkelivertaisarvioitu

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@article{43366e71a94545e8b66dcdbb8dbaa9ac,
title = "Differential inter-subject correlation of brain activity when kinship is a variable in moral dilemma",
abstract = "Previous behavioural studies have shown that humans act more altruistically towards kin. Whether and how knowledge of genetic relatedness translates into differential neurocognitive evaluation of observed social interactions has remained an open question. Here, we investigated how the human brain is engaged when viewing a moral dilemma between genetic vs. non-genetic sisters. During functional magnetic resonance imaging, a movie was shown, depicting refusal of organ donation between two sisters, with subjects guided to believe the sisters were related either genetically or by adoption. Although 90{\%} of the subjects self-reported that genetic relationship was not relevant, their brain activity told a different story. Comparing correlations of brain activity across all subject pairs between the two viewing conditions, we found significantly stronger inter-subject correlations in insula, cingulate, medial and lateral prefrontal, superior temporal, and superior parietal cortices, when the subjects believed that the sisters were genetically related. Cognitive functions previously associated with these areas include moral and emotional conflict regulation, decision making, and mentalizing, suggesting more similar engagement of such functions when observing refusal of altruism from a genetic sister. Our results show that mere knowledge of a genetic relationship between interacting persons robustly modulates social cognition of the perceiver.",
author = "Mareike Bacha-Trams and Enrico Glerean and Robin Dunbar and Lahnakoski, {Juha M.} and Elisa Ryypp{\"o} and Mikko Sams and J{\"a}{\"a}skel{\"a}inen, {Iiro P.}",
year = "2017",
month = "12",
day = "1",
doi = "10.1038/s41598-017-14323-x",
language = "English",
volume = "7",
pages = "1--16",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "Nature Publishing Group",
number = "1",

}

RIS - Lataa

TY - JOUR

T1 - Differential inter-subject correlation of brain activity when kinship is a variable in moral dilemma

AU - Bacha-Trams, Mareike

AU - Glerean, Enrico

AU - Dunbar, Robin

AU - Lahnakoski, Juha M.

AU - Ryyppö, Elisa

AU - Sams, Mikko

AU - Jääskeläinen, Iiro P.

PY - 2017/12/1

Y1 - 2017/12/1

N2 - Previous behavioural studies have shown that humans act more altruistically towards kin. Whether and how knowledge of genetic relatedness translates into differential neurocognitive evaluation of observed social interactions has remained an open question. Here, we investigated how the human brain is engaged when viewing a moral dilemma between genetic vs. non-genetic sisters. During functional magnetic resonance imaging, a movie was shown, depicting refusal of organ donation between two sisters, with subjects guided to believe the sisters were related either genetically or by adoption. Although 90% of the subjects self-reported that genetic relationship was not relevant, their brain activity told a different story. Comparing correlations of brain activity across all subject pairs between the two viewing conditions, we found significantly stronger inter-subject correlations in insula, cingulate, medial and lateral prefrontal, superior temporal, and superior parietal cortices, when the subjects believed that the sisters were genetically related. Cognitive functions previously associated with these areas include moral and emotional conflict regulation, decision making, and mentalizing, suggesting more similar engagement of such functions when observing refusal of altruism from a genetic sister. Our results show that mere knowledge of a genetic relationship between interacting persons robustly modulates social cognition of the perceiver.

AB - Previous behavioural studies have shown that humans act more altruistically towards kin. Whether and how knowledge of genetic relatedness translates into differential neurocognitive evaluation of observed social interactions has remained an open question. Here, we investigated how the human brain is engaged when viewing a moral dilemma between genetic vs. non-genetic sisters. During functional magnetic resonance imaging, a movie was shown, depicting refusal of organ donation between two sisters, with subjects guided to believe the sisters were related either genetically or by adoption. Although 90% of the subjects self-reported that genetic relationship was not relevant, their brain activity told a different story. Comparing correlations of brain activity across all subject pairs between the two viewing conditions, we found significantly stronger inter-subject correlations in insula, cingulate, medial and lateral prefrontal, superior temporal, and superior parietal cortices, when the subjects believed that the sisters were genetically related. Cognitive functions previously associated with these areas include moral and emotional conflict regulation, decision making, and mentalizing, suggesting more similar engagement of such functions when observing refusal of altruism from a genetic sister. Our results show that mere knowledge of a genetic relationship between interacting persons robustly modulates social cognition of the perceiver.

UR - http://www.scopus.com/inward/record.url?scp=85032498460&partnerID=8YFLogxK

U2 - 10.1038/s41598-017-14323-x

DO - 10.1038/s41598-017-14323-x

M3 - Article

AN - SCOPUS:85032498460

VL - 7

SP - 1

EP - 16

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 14244

ER -

ID: 16043563