Liquid-liquid phase transition known as coacervation of resilin-like-peptide fusion proteins containing different terminal domains were investigated. Two different modular proteins were designed and produced and their behavior were compared to a resilin-like-peptide without terminal domains. The size of the particle-like coacervates was modulated by the protein concentration, pH and temperature. The morphology and three-dimensional (3D) structural details of the coacervate particles were investigated by cryogenic transmission electron microscopy (cryo-TEM) and tomography (cryo-ET) reconstruction. Selective adhesion of the coacervates on cellulose and graphene surfaces was demonstrated.
SormenjälkiSukella tutkimusaiheisiin 'Coacervation of resilin fusion proteins containing terminal functionalities'. Ne muodostavat yhdessä ainutlaatuisen sormenjäljen.
- 1 Päättynyt
HYBER: Suomen Akatemian Biosynteettisten hybridimateriaalien molekyylimuokkauksen huippuyksikkö (2014-2019)
01/01/2017 → 31/12/2019
Projekti: Academy of Finland: Other research funding