Bioinspired lubricating films of cellulose nanofibrils and hyaluronic acid

Tutkimustuotos: Lehtiartikkelivertaisarvioitu

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The development of materials that combine the excellent mechanical strength of cellulose nanofibrils (CNF) with the lubricating properties of hyaluronic acid (HA) is a new, promising approach to cartilage implants not explored so far. A simple, solvent-free method to produce a very lubricating, strong cellulosic material by covalently attaching HA to the surface of CNF films is described in this work. A detailed analysis of the tribological properties of the CNF films with and without HA is also presented. Surface and friction forces at micro/nanoscale between model hard surfaces (glass microspheres) and the CNF thin films were measured using an atomic force microscope and the colloid probe technique. The effect of HA attachment, the pH and the ionic strength of the aqueous medium on the forces was examined. Excellent lubrication was observed for CNF films with HA attached in conditions where the HA layer was highly hydrated. These results pave the way for the development of new nanocellulose-based materials with good lubrication properties that could be used in biomedical applications. (C) 2015 Elsevier B.V. All rights reserved.

Yksityiskohdat

AlkuperäiskieliEnglanti
Sivut86-93
Sivumäärä8
JulkaisuColloids and Surfaces B: Biointerfaces
Vuosikerta138
TilaJulkaistu - 1 helmikuuta 2016
OKM-julkaisutyyppiA1 Julkaistu artikkeli, soviteltu

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