A Sensor Interface for Neurochemical Signal Acquisition

Tutkimustuotos: Artikkeli kirjassa/konferenssijulkaisussavertaisarvioitu

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This paper describes the design of an integrated sensor interface for neurochemical signal acquisition. Neurochemicals undergo oxidation and reduction reactions in the presence of an action potential. Thus, knowledge of the oxidation and reduction potentials of neurochemicals is important in the neurostimulation treatment of neurological and neurodegenerative diseases. The sensor interface circuit utilizes a mixed-signal design to detect the induced current from the neurochemical, in response to an applied voltage. The circuit is fabricated in 65nm CMOS technology and supports a wide input current range of ±1.2μA with a current resolution of 85.4pA, enabling detection of neurochemicals within the supported current range. Measured results with dopamine concentration of 500nMol demonstrate the ability of the sensor interface circuit to detect oxidation and reduction current peaks, indicating the release times and the required oxidation and reduction potentials for neurostimulation of the neurochemical.

Yksityiskohdat

AlkuperäiskieliEnglanti
Otsikko2019 IEEE 62nd International Midwest Symposium on Circuits and Systems, MWSCAS 2019
TilaJulkaistu - 1 elokuuta 2019
OKM-julkaisutyyppiA4 Artikkeli konferenssijulkaisuussa
TapahtumaInternational Midwest Symposium on Circuits and Systems - Dallas, Yhdysvallat
Kesto: 4 elokuuta 20197 elokuuta 2019
Konferenssinumero: 62

Julkaisusarja

NimiConference proceedings : Midwest Symposium on Circuits and Systems
ISSN (painettu)1548-3746
ISSN (elektroninen)1558-3899

Conference

ConferenceInternational Midwest Symposium on Circuits and Systems
LyhennettäMWSCAS
MaaYhdysvallat
KaupunkiDallas
Ajanjakso04/08/201907/08/2019

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