YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE

JOHN MCBRIDE; ELENA BREVNOVA; MARK MELLON; ALLAN FROEHLICH; KRISTEN DELEAULT; VINEET RAJGARHIA; RIAAN DEN HAAN; Merja Penttilä; MARJA ILMEN; MATTI SIIKA-AHO; JAANA UUSITALO; A STONEHOUSE EMILY; ALAN GILBERT; HAOWEN XU; DEIDRE WILLES; JOHN BARDSLEY; ANU KOIVULA; SANNI VOUTILAINEN

YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE

JOHN MCBRIDE (Inventor), ELENA BREVNOVA (Inventor), MARK MELLON (Inventor), ALLAN FROEHLICH (Inventor), KRISTEN DELEAULT (Inventor), VINEET RAJGARHIA (Inventor), RIAAN DEN HAAN (Inventor), Merja Penttilä (Inventor), MARJA ILMEN (Inventor), MATTI SIIKA-AHO (Inventor), JAANA UUSITALO (Inventor), A STONEHOUSE EMILY (Inventor), ALAN GILBERT (Inventor), HAOWEN XU (Inventor), DEIDRE WILLES (Inventor), JOHN BARDSLEY (Inventor), ANU KOIVULA (Inventor), SANNI VOUTILAINEN (Inventor)

Department of Bioproducts and Biosystems

Lallemand Hungary Liquidity Management LLC

Research output: Patent

Abstract

The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluveryomyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.

Original language	English
Patent number	US2016010117
IPC	C12N 9/ 42 A I
Priority date	01/07/2015
Publication status	Published - 14 Jan 2016
MoE publication type	H1 Granted patent

Bioeconomy Research Infrastructure
Seppälä, J. (Manager)
School of Chemical Engineering
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Cite this

MCBRIDE, JOHN., BREVNOVA, ELENA., MELLON, MARK., FROEHLICH, ALLAN., DELEAULT, KRISTEN., RAJGARHIA, VINEET., DEN HAAN, RIAAN., Penttilä, M., ILMEN, MARJA., SIIKA-AHO, MATTI., UUSITALO, JAANA., STONEHOUSE EMILY, A., GILBERT, ALAN., XU, HAOWEN., WILLES, DEIDRE., BARDSLEY, JOHN., KOIVULA, ANU., & VOUTILAINEN, SANNI. (2016). YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE. (Patent No. US2016010117).

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title = "YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE",

abstract = "The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluveryomyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.",

author = "JOHN MCBRIDE and ELENA BREVNOVA and MARK MELLON and ALLAN FROEHLICH and KRISTEN DELEAULT and VINEET RAJGARHIA and {DEN HAAN}, RIAAN and Merja Penttil{\"a} and MARJA ILMEN and MATTI SIIKA-AHO and JAANA UUSITALO and {STONEHOUSE EMILY}, A and ALAN GILBERT and HAOWEN XU and DEIDRE WILLES and JOHN BARDSLEY and ANU KOIVULA and SANNI VOUTILAINEN",

year = "2016",

month = jan,

day = "14",

language = "English",

type = "Patent",

note = "US2016010117; C12N 9/ 42 A I",

}

MCBRIDE, JOHN, BREVNOVA, ELENA, MELLON, MARK, FROEHLICH, ALLAN, DELEAULT, KRISTEN, RAJGARHIA, VINEET, DEN HAAN, RIAAN, Penttilä, M, ILMEN, MARJA, SIIKA-AHO, MATTI, UUSITALO, JAANA, STONEHOUSE EMILY, A, GILBERT, ALAN, XU, HAOWEN, WILLES, DEIDRE, BARDSLEY, JOHN, KOIVULA, ANU & VOUTILAINEN, SANNI Jan. 14 2016, YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE, Patent No. US2016010117.

TY - PAT

T1 - YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE

AU - MCBRIDE, JOHN

AU - BREVNOVA, ELENA

AU - MELLON, MARK

AU - FROEHLICH, ALLAN

AU - DELEAULT, KRISTEN

AU - RAJGARHIA, VINEET

AU - DEN HAAN, RIAAN

AU - Penttilä, Merja

AU - ILMEN, MARJA

AU - SIIKA-AHO, MATTI

AU - UUSITALO, JAANA

AU - STONEHOUSE EMILY, A

AU - GILBERT, ALAN

AU - XU, HAOWEN

AU - WILLES, DEIDRE

AU - BARDSLEY, JOHN

AU - KOIVULA, ANU

AU - VOUTILAINEN, SANNI

PY - 2016/1/14

Y1 - 2016/1/14

N2 - The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluveryomyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.

AB - The present invention is directed to cellulytic host cells. The host cells of the invention expressing heterologous cellulases and are able to produce ethanol from cellulose. According to the invention, host cells expressing a combination of heterologous cellulases can be used to produce ethanol from cellulose. In addition, multiple host cells expressing different heterlogous cellulases can be co-cultured together and used to produce ethanol from cellulose. Furthermore, the invention demonstrates for the first time the ability of Kluveryomyces to produce ethanol from cellulose. The yeast strains and co-cultures of yeast strains of the invention can be used to produce ethanol on their own, or can also be used in combination with externally added cellulases to increase the efficiency of saccharification and fermentation processes.

M3 - Patent

M1 - US2016010117

ER -

YEAST EXPRESSING CELLULASES FOR SIMULTANEOUS SACCHARIFICATION AND FERMENTATION USING CELLULOSE

Abstract

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