Viscoelastic interaction between intraocular microrobots and vitreous humor: A finite element approach

Zhongkui Wang, Juho Pokki, Olgac Ergeneman, Bradley J. Nelson, Shinichi Hirai

Research output: Chapter in Book/Report/Conference proceedingConference article in proceedingsScientificpeer-review

4 Citations (Scopus)

Abstract

Vitreous humor exhibits complex biomechanical properties and determination of these properties is essential for designing ophthalmic biomedical microdevices. In this paper, the viscoelastic properties of porcine vitreous humor were studied based on ex vivo creep experiments, in which a microrobot was magnetically actuated inside the vitreous. A three-dimensional (3D) finite element (FE) model was proposed to simulate the viscoelastic interaction between the microrobot and porcine vitreous humor. An optimization-based method was employed to estimate the viscoelastic parameters of the vitreous humor. The proposed model successfully validated the experimental measurements. The estimated parameters were compared with published data in literature. The model was then used to study the shape-dependent interaction of the microrobot with the vitreous humor. The methods presented in this paper can be used for the optimization of ophthalmic microrobots and microsurgical tools.

Original languageEnglish
Title of host publication2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2013
Pages4937-4940
Number of pages4
DOIs
Publication statusPublished - 2013
MoE publication typeA4 Conference publication
EventAnnual International Conference of the IEEE Engineering in Medicine and Biology Society - Osaka, Japan
Duration: 3 Jul 20137 Jul 2013
Conference number: 35

Publication series

NameProceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS
ISSN (Print)1557-170X

Conference

ConferenceAnnual International Conference of the IEEE Engineering in Medicine and Biology Society
Abbreviated titleEMBC
Country/TerritoryJapan
CityOsaka
Period03/07/201307/07/2013

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