Ultrasensitive and label-free molecular-level detection enabled by light phase control in magnetoplasmonic nanoantennas

Nicolò Maccaferri, Keith E. Gregorczyk, Thales V.A.G. de Oliveira, Mikko Kataja, Sebastiaan van Dijken, Zhaleh Pirzadeh, Alexandre Dmitriev, Johan Åkerman, Mato Knez, Paolo Vavassori

Research output: Contribution to journalArticleScientificpeer-review

121 Citations (Scopus)
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Abstract

Systems allowing label-free molecular detection are expected to have enormous impact on biochemical sciences. Research focuses on materials and technologies based on exploiting localized surface plasmon resonances in metallic nanostructures. The reason for this focused attention is their suitability for single-molecule sensing, arising from intrinsically nanoscopic sensing volume and the high sensitivity to the local environment. Here we propose an alternative route, which enables radically improved sensitivity compared with recently reported plasmon-based sensors. Such high sensitivity is achieved by exploiting the control of the phase of light in magnetoplasmonic nanoantennas. We demonstrate a manifold improvement of refractometric sensing figure-of-merit. Most remarkably, we show a raw surface sensitivity (that is, without applying fitting procedures) of two orders of magnitude higher than the current values reported for nanoplasmonic sensors. Such sensitivity corresponds to a mass of ~0.8 ag per nanoantenna of polyamide-6.6 (n=1.51), which is representative for a large variety of polymers, peptides and proteins.
Original languageEnglish
Article number6150
Pages (from-to)1-8
Number of pages8
JournalNature Communications
Volume6
DOIs
Publication statusPublished - Feb 2015
MoE publication typeA1 Journal article-refereed

Keywords

  • magnetism
  • molecular detection
  • plasmonics

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