Ultrafast inverse imaging techniques for fMRI

Research output: Contribution to journalReview ArticleScientificpeer-review


  • Fa Hsuan Lin
  • Kevin W K Tsai
  • Ying-Hua Chu
  • Thomas Witzel
  • Aapo Nummenmaa
  • Tommi Raij
  • Jyrki Ahveninen
  • Wen-Jui Kuo
  • John W. Belliveau

Research units

  • National Taiwan University
  • Harvard University
  • National Yang-Ming University


Inverse imaging (InI) supercharges the sampling rate of traditional functional MRI 10-100 fold at a cost of a moderate reduction in spatial resolution. The technique is inspired by similarities between multi-sensor magnetoencephalography (MEG) and highly parallel radio-frequency (RF) MRI detector arrays. Using presently available 32-channel head coils at 3T, InI can be sampled at 10. Hz and provides about 5-mm cortical spatial resolution with whole-brain coverage. Here we discuss the present applications of InI, as well as potential future challenges and opportunities in further improving its spatiotemporal resolution and sensitivity. InI may become a helpful tool for clinicians and neuroscientists for revealing the complex dynamics of brain functions during task-related and resting states.


Original languageEnglish
Pages (from-to)699-705
Number of pages7
Issue number2
Publication statusPublished - 15 Aug 2012
MoE publication typeA2 Review article in a scientific journal

    Research areas

  • Fast imaging, InI, Inverse problem, Parallel imaging

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