U wave features in body surface potential mapping in post-myocardial infarction patients

Bei Wang*, Petri Korhonen, Ilkka Tierala, Helena Hänninen, Heikki Väänänen, Lauri Toivonen

*Corresponding author for this work

    Research output: Contribution to journalArticleScientificpeer-review

    1 Citation (Scopus)


    BackgroundThe data on U wave features in post-myocardial infarction (MI) remain sparse. We employed 120-lead body surface potential mapping (BSPM) to explore the U wave in patients with remote MI. MethodsSixty post-MI patients and 46 healthy controls were examined. After signal averaging, the polarity changes of U wave related to the T wave were analyzed, and the spatial and temporal U wave parameters were computed. ResultsFour types of patterns based on T and U polarity were recognized. A pattern with positive T and U waves was related to better ventricular function. The study groups did not differ as regards to Tend-Uapex and Tapex-Uapex intervals whereas Uapex-Uend was significantly longer in MI patients (110 ± 20 ms vs. 100 ± 13 ms, P = 0.004). MI patients had significantly higher U wave maximum amplitude (70 ± 30 μV vs. 50 ± 20 μV, P < 0.001), and U integral area (3.96 ± 1.50 μV·s vs. 3.17 ± 0.99 μV·s, P = 0.002), but lower corresponding T wave parameter values, thus resulting into higher U/T maximum amplitude and area ratios (0.16 ± 0.10 vs. 0.09 ± 0.04, P < 0.001; and 0.13 ± 0.06 vs. 0.09 ± 0.03, P < 0.001). In comparison to 12-lead ECG, BSPM covering the entire thorax enhanced the detection of U waves. ConclusionMI tends to increase the U amplitude and prolong the later part of U wave duration thus augmenting the U wave. The size and location of infarction were associated with specific T and U wave polarity patterns.

    Original languageEnglish
    Pages (from-to)538-546
    Number of pages9
    JournalAnnals of Noninvasive Electrocardiology
    Issue number6
    Publication statusPublished - Nov 2013
    MoE publication typeA1 Journal article-refereed


    • body surface potential mapping
    • myocardial infarction
    • repolarization
    • U wave


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