Trapping, manipulation, and crystallization of live cells using magnetofluidic tweezers

Research output: Contribution to journalArticle

Researchers

Research units

  • Northwestern University
  • Ulsan National Institute of Science and Technology
  • Indian Institute of Science Education and Research Pune

Abstract

Live mammalian cells are captured and manipulated in magneto-fluidic traps created in a suspension of biocompatible, magnetic nanoparticles by a coaxial magnetic/non-magnetic "micropen''. Upon activation by an external electromagnet, the pen creates microscale gradients of magnetic field and nanoparticle concentration that translate into directional and confining forces acting on the cells. Both individual cells and cell collections can be trapped by this method, allowing, for instance, for the formation of regularly shaped cell assemblies. The method does not entail any local heating artifacts and does not require magnetic tagging of the cells.

Details

Original languageEnglish
Pages (from-to)50-54
Number of pages5
JournalNanoscale Horizons
Volume2
Issue number1
Publication statusPublished - 2017
MoE publication typeA1 Journal article-refereed

    Research areas

  • BACTERIA, CULTURE

ID: 15917865