Transient sensitivity reduction and biphasic photoresponses observed when frog retinal rods are oxidized

K. Donner, S. Hemilä, Ari Koskelainen

Research output: Contribution to journalArticleScientificpeer-review

Abstract

1. Rod photoresponses and the effects of oxidation have been studied by recording either the transretinal voltage in aspartate-treated retinas or the outer segment current of single rods.
2. Oxidizing conditions transiently decreased, reducing conditions increased sensitivity.
3. Biphasic photoresponses were seen when the level of oxidation was rising and also in some other sensitivity-depressing conditions.
4. A model is proposed which explains the biphasic responses in terms of sensitivity differences between the tip and the base of the rod outer segment.
Original languageEnglish
Pages (from-to)749-756
JournalCOMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY A: MOLECULAR AND INTEGRATIVE PHYSIOLOGY
Volume87
Issue number3
DOIs
Publication statusPublished - 1987
MoE publication typeA1 Journal article-refereed

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