Toxicities of detergents used in cleaning chemicals and hygiene products in a test battery of ex vivo and in vitro assays

Research output: Chapter in Book/Report/Conference proceedingChapterScientific


Research units

  • University of Pannonia
  • Tallinn University of Technology


Five synthetic surfactants used as detergents in cleaning chemicals and hygiene products were selected to test their In vivo and Ex vivo toxicity. The toxicity of one anionic detergent (SDS), one cationic detergent (DDDAC) and three non-ionic detergents (TWEEN 80, triton X-100, genapol X-080) was tested with boar spermatozoa (4 Ex Vivo assays) and PK-15 porcine kidney cells (4 In Vivo assays). The reference toxin used was triclosan (biocide). The results revealed a characteristic toxicity profile for each detergent. The detergents toxicity from most to least toxic was as follow: DDDAC > genapol X-080 > triclosan > triton x-100 > SDS > TWEEN 80. The results also showed that mitochondrial toxicity -measured as acceleration of glucose consumption-was detected for genapol X-080, DDAC and triclosan but not for TWEEN 80.


Original languageEnglish
Title of host publicationSisäilmastoseminaari 2019
Subtitle of host publicationSisäilmayhdistys raportti 37
EditorsMervi Ahola, Anna Merikari
Publication statusPublished - 2019
MoE publication typeB2 Part of a book or another research book
EventSisäilmastoseminaari - Helsinki, Finland
Duration: 14 Mar 201914 Mar 2019
Conference number: 34

Publication series

NameSIY raportti
PublisherSisäilmayhdistys ry
ISSN (Print)1237-1866



ID: 40181476