Abstract
Five synthetic surfactants used as detergents in cleaning chemicals and hygiene products were selected to test their In vivo and Ex vivo toxicity. The toxicity of one anionic detergent (SDS), one cationic detergent (DDDAC) and three non-ionic detergents (TWEEN 80, triton X-100, genapol X-080) was tested with boar spermatozoa (4 Ex Vivo assays) and PK-15 porcine kidney cells (4 In Vivo assays). The reference toxin used was triclosan (biocide). The results revealed a characteristic toxicity profile for each detergent. The detergents toxicity from most to least toxic was as follow: DDDAC > genapol X-080 > triclosan > triton x-100 > SDS > TWEEN 80. The results also showed that mitochondrial toxicity -measured as acceleration of glucose consumption-was detected for genapol X-080, DDAC and triclosan but not for TWEEN 80.
| Original language | English |
|---|---|
| Title of host publication | Sisäilmastoseminaari 2019 |
| Subtitle of host publication | Sisäilmayhdistys raportti 37 |
| Editors | Mervi Ahola, Anna Merikari |
| Publisher | SIY Sisäilmatieto Oy |
| Pages | 297-302 |
| ISBN (Electronic) | 978-952-5236-49-1 |
| Publication status | Published - 2019 |
| MoE publication type | B2 Book section |
| Event | Sisäilmastoseminaari - Helsinki, Finland Duration: 14 Mar 2019 → 14 Mar 2019 Conference number: 34 |
Publication series
| Name | SIY raportti |
|---|---|
| Publisher | Sisäilmayhdistys ry |
| Number | 37 |
| ISSN (Print) | 1237-1866 |
Seminar
| Seminar | Sisäilmastoseminaari |
|---|---|
| Country/Territory | Finland |
| City | Helsinki |
| Period | 14/03/2019 → 14/03/2019 |