Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity

Mika Pulkkinen; Jere Pikkarainen; Thomas Wirth; Tommy Tarvainen; Vesa Haapa-aho; Harri Korhonen; Jukka Seppälä; Kristiina Järvinen

doi:10.1016/j.ejpb.2008.04.018

Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity

Mika Pulkkinen, Jere Pikkarainen, Thomas Wirth, Tommy Tarvainen, Vesa Haapa-aho, Harri Korhonen, Jukka Seppälä, Kristiina Järvinen

University of Eastern Finland

Research output: Contribution to journal › Article › Scientific › peer-review

127 Citations (Scopus)

Original language	English
Pages (from-to)	66-74
Number of pages	9
Journal	European Journal of Pharmaceutics and Biopharmaceutics
Volume	70
Issue number	1
DOIs	https://doi.org/10.1016/j.ejpb.2008.04.018
Publication status	Published - 2008
MoE publication type	A1 Journal article-refereed

Keywords

in vitro anticancer activity
PLA-PEG nanoparticles

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10.1016/j.ejpb.2008.04.018

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Pulkkinen, M., Pikkarainen, J., Wirth, T., Tarvainen, T., Haapa-aho, V., Korhonen, H., Seppälä, J., & Järvinen, K. (2008). Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity. European Journal of Pharmaceutics and Biopharmaceutics, 70(1), 66-74. https://doi.org/10.1016/j.ejpb.2008.04.018

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title = "Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity",

keywords = "in vitro anticancer activity, PLA-PEG nanoparticles, in vitro anticancer activity, PLA-PEG nanoparticles, in vitro anticancer activity, PLA-PEG nanoparticles",

author = "Mika Pulkkinen and Jere Pikkarainen and Thomas Wirth and Tommy Tarvainen and Vesa Haapa-aho and Harri Korhonen and Jukka Sepp{\"a}l{\"a} and Kristiina J{\"a}rvinen",

year = "2008",

doi = "10.1016/j.ejpb.2008.04.018",

language = "English",

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journal = "European Journal of Pharmaceutics and Biopharmaceutics",

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Pulkkinen, M, Pikkarainen, J, Wirth, T, Tarvainen, T, Haapa-aho, V, Korhonen, H, Seppälä, J & Järvinen, K 2008, 'Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity', European Journal of Pharmaceutics and Biopharmaceutics, vol. 70, no. 1, pp. 66-74. https://doi.org/10.1016/j.ejpb.2008.04.018

Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity. / Pulkkinen, Mika; Pikkarainen, Jere; Wirth, Thomas et al.
In: European Journal of Pharmaceutics and Biopharmaceutics, Vol. 70, No. 1, 2008, p. 66-74.

Research output: Contribution to journal › Article › Scientific › peer-review

TY - JOUR

T1 - Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology

T2 - Formulation development and in vitro anticancer activity

AU - Pulkkinen, Mika

AU - Pikkarainen, Jere

AU - Wirth, Thomas

AU - Tarvainen, Tommy

AU - Haapa-aho, Vesa

AU - Korhonen, Harri

AU - Seppälä, Jukka

AU - Järvinen, Kristiina

PY - 2008

Y1 - 2008

KW - in vitro anticancer activity

KW - PLA-PEG nanoparticles

KW - in vitro anticancer activity

KW - PLA-PEG nanoparticles

KW - in vitro anticancer activity

KW - PLA-PEG nanoparticles

UR - https://www.scopus.com/pages/publications/50149113005

U2 - 10.1016/j.ejpb.2008.04.018

DO - 10.1016/j.ejpb.2008.04.018

M3 - Article

SN - 0939-6411

VL - 70

SP - 66

EP - 74

JO - European Journal of Pharmaceutics and Biopharmaceutics

JF - European Journal of Pharmaceutics and Biopharmaceutics

IS - 1

ER -

Three-step tumor targeting of paclitaxel using biotinylated PLA-PEG nanoparticles and avidin-biotin technology: Formulation development and in vitro anticancer activity

Keywords

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