Three-Dimensional Uracil Network with Sodium as a Linker

Zivile Giedraityte; Olga Lopez-Acevedo; Leonardo A. Espinosa Leal; Ville Pale; Jani Sainio; Tripurari S. Tripathi; Maarit Karppinen

doi:10.1021/acs.jpcc.6b08986

Three-Dimensional Uracil Network with Sodium as a Linker

Zivile Giedraityte
, Olga Lopez-Acevedo
, Leonardo A. Espinosa Leal
, Ville Pale
, Jani Sainio
, Tripurari S. Tripathi
, Maarit Karppinen^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › Scientific › peer-review

23 Citations (Scopus)

544 Downloads (Pure)

Abstract

Here we show that uracil and sodium form a three-dimensional metal-mediated nucleic acid network; it is grown in atomic/molecular layer-by-layer manner using the atomic/molecular layer deposition (ALD/MLD) thin-film technique. The long-range ordered Na-uracil crystalline structure is evidenced as sharp Bragg reflections. Based on density functional theory (DFT) calculations, a tetrameric-like crystal structure is proposed. Na-uracil thin films are fluorescent with a lifetime 3 orders of magnitude higher than commonly seen for nucleic acid molecules. Our method provides a new approach to designing 3D nucleic acid-metal nanostructures.

Original language	English
Pages (from-to)	26342-26349
Number of pages	8
Journal	Journal of Physical Chemistry C
Volume	120
Issue number	46
DOIs	https://doi.org/10.1021/acs.jpcc.6b08986
Publication status	Published - 24 Nov 2016
MoE publication type	A1 Journal article-refereed

Funding

The present work has received funding from the European Research Council under the European Union's Seventh Framework Programme (FP/2007-2013)/ERC Advanced Grant Agreement (No. 339478), Academy of Finland (No. 285972), and Aalto ELEC Doctoral School. We acknowledge the provision of facilities and technical support by Aalto University at OtaNano-Nanomicroscopy Center (Aalto-NMC). Armi Tiihonen is thanked for taking pictures of Nauracil thin films under UV light. Kenneth Pennington is thanked for his advice.

Keywords

ATOMIC LAYER DEPOSITION
RAY CRYSTAL-STRUCTURE
GAS-PHASE
INFRARED-SPECTRA
AQUEOUS-SOLUTION
METAL-SURFACES
EXCITED-STATE
THIN-FILMS
RNA BASES
DNA

Access to Document

10.1021/acs.jpcc.6b08986

ERC-25-acceptedAccepted author manuscript, 2.16 MBLicence: Unspecified
ERC-25-accepted-Supporting-InfoFinal published version, 7.87 MBLicence: Unspecified

Molecular-Layer-Engineered Inorganic-Organic Hybrid Materials
Karppinen, M. (Principal investigator), Johansson, L.-S. (Project Member), Hagen, D. (Project Member), Medina, E. (Project Member), Tripathi, T. (Project Member), Lepikko, S. (Project Member), Tenhunen, M. (Project Member), Multia, J. (Project Member), Haggren, A. (Project Member), Puikkonen, P. (Project Member), Jin, H. (Project Member), Niemelä, J.-P. (Project Member), Vähä-Pietilä, E. (Project Member), Krahl, F. (Project Member), Matikainen, A. (Project Member), Heiska, J. (Project Member), Khayyami, A. (Project Member), Tiittanen, T. (Project Member), Mustonen, O. (Project Member), Aleksandrova, I. (Project Member), Stenholm, M. (Project Member), Thomas, C. (Project Member), Nisula, M. (Project Member), Marin, G. (Project Member), Giedraityte, Z. (Project Member), Ghazy, A. (Project Member), Chou, T.-L. (Project Member), Philip, A. (Project Member), Safdar, M. (Project Member) & Ahvenniemi, E. (Project Member)
23/12/2013 → 31/01/2019
Project: EU: ERC grants

Raw Materials Research Infrastructure
Karppinen, M. (Manager)
School of Chemical Engineering
Facility/equipment: Facility

Cite this

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title = "Three-Dimensional Uracil Network with Sodium as a Linker",

abstract = "Here we show that uracil and sodium form a three-dimensional metal-mediated nucleic acid network; it is grown in atomic/molecular layer-by-layer manner using the atomic/molecular layer deposition (ALD/MLD) thin-film technique. The long-range ordered Na-uracil crystalline structure is evidenced as sharp Bragg reflections. Based on density functional theory (DFT) calculations, a tetrameric-like crystal structure is proposed. Na-uracil thin films are fluorescent with a lifetime 3 orders of magnitude higher than commonly seen for nucleic acid molecules. Our method provides a new approach to designing 3D nucleic acid-metal nanostructures.",

keywords = "ATOMIC LAYER DEPOSITION, RAY CRYSTAL-STRUCTURE, GAS-PHASE, INFRARED-SPECTRA, AQUEOUS-SOLUTION, METAL-SURFACES, EXCITED-STATE, THIN-FILMS, RNA BASES, DNA",

author = "Zivile Giedraityte and Olga Lopez-Acevedo and \{Espinosa Leal\}, \{Leonardo A.\} and Ville Pale and Jani Sainio and Tripathi, \{Tripurari S.\} and Maarit Karppinen",

note = "| openaire: EC/FP7/339478/EU//LAYERENG-HYBMAT ",

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doi = "10.1021/acs.jpcc.6b08986",

language = "English",

volume = "120",

pages = "26342--26349",

journal = "Journal of Physical Chemistry C",

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T1 - Three-Dimensional Uracil Network with Sodium as a Linker

AU - Giedraityte, Zivile

AU - Lopez-Acevedo, Olga

AU - Espinosa Leal, Leonardo A.

AU - Pale, Ville

AU - Sainio, Jani

AU - Tripathi, Tripurari S.

AU - Karppinen, Maarit

N1 - | openaire: EC/FP7/339478/EU//LAYERENG-HYBMAT

PY - 2016/11/24

Y1 - 2016/11/24

N2 - Here we show that uracil and sodium form a three-dimensional metal-mediated nucleic acid network; it is grown in atomic/molecular layer-by-layer manner using the atomic/molecular layer deposition (ALD/MLD) thin-film technique. The long-range ordered Na-uracil crystalline structure is evidenced as sharp Bragg reflections. Based on density functional theory (DFT) calculations, a tetrameric-like crystal structure is proposed. Na-uracil thin films are fluorescent with a lifetime 3 orders of magnitude higher than commonly seen for nucleic acid molecules. Our method provides a new approach to designing 3D nucleic acid-metal nanostructures.

AB - Here we show that uracil and sodium form a three-dimensional metal-mediated nucleic acid network; it is grown in atomic/molecular layer-by-layer manner using the atomic/molecular layer deposition (ALD/MLD) thin-film technique. The long-range ordered Na-uracil crystalline structure is evidenced as sharp Bragg reflections. Based on density functional theory (DFT) calculations, a tetrameric-like crystal structure is proposed. Na-uracil thin films are fluorescent with a lifetime 3 orders of magnitude higher than commonly seen for nucleic acid molecules. Our method provides a new approach to designing 3D nucleic acid-metal nanostructures.

KW - ATOMIC LAYER DEPOSITION

KW - RAY CRYSTAL-STRUCTURE

KW - GAS-PHASE

KW - INFRARED-SPECTRA

KW - AQUEOUS-SOLUTION

KW - METAL-SURFACES

KW - EXCITED-STATE

KW - THIN-FILMS

KW - RNA BASES

KW - DNA

U2 - 10.1021/acs.jpcc.6b08986

DO - 10.1021/acs.jpcc.6b08986

M3 - Article

SN - 1932-7447

VL - 120

SP - 26342

EP - 26349

JO - Journal of Physical Chemistry C

JF - Journal of Physical Chemistry C

IS - 46

ER -

Three-Dimensional Uracil Network with Sodium as a Linker

Abstract

Funding

Keywords

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Molecular-Layer-Engineered Inorganic-Organic Hybrid Materials

Equipment

Raw Materials Research Infrastructure

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