The Cambridge Centre for Ageing and Neuroscience (Cam-CAN) data repository: Structural and functional MRI, MEG, and cognitive data from a cross-sectional adult lifespan sample

Jason R. Taylor*, Nitin Williams, Rhodri Cusack, Tibor Auer, Meredith A. Shafto, Marie Dixon, Lorraine K. Tyler, Cam-Can, Richard N. Henson

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

114 Citations (Scopus)

Abstract

This paper describes the data repository for the Cambridge Centre for Ageing and Neuroscience (Cam-CAN) initial study cohort. The Cam-CAN Stage 2 repository contains multi-modal (MRI, MEG, and cognitive-behavioural) data from a large (approximately N = 700), cross-sectional adult lifespan (18-87 years old) population-based sample. The study is designed to characterise age-related changes in cognition and brain structure and function, and to uncover the neurocognitive mechanisms that support healthy cognitive ageing. The database contains raw and preprocessed structural MRI, functional MRI (active tasks and resting state), and MEG data (active tasks and resting state), as well as derived scores from cognitive behavioural experiments spanning five broad domains (attention, emotion, action, language, and memory), and demographic and neuropsychological data. The dataset thus provides a depth of neurocognitive phenotyping that is currently unparalleled, enabling integrative analyses of age-related changes in brain structure, brain function, and cognition, and providing a testbed for novel analyses of multi-modal neuroimaging data. (C) 2015 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license.

Original languageEnglish
Pages (from-to)262-269
Number of pages8
JournalNeuroImage
Volume144
DOIs
Publication statusPublished - 1 Jan 2017
MoE publication typeA1 Journal article-refereed

Keywords

  • Data repository
  • Brain imaging
  • Magnetic resonance imaging
  • Magnetoencephalography
  • Cognition
  • Ageing
  • EMOTION RECOGNITION
  • MEMORY
  • FMRI
  • INTELLIGENCE
  • SYSTEM
  • CORTEX
  • DAMAGE
  • STATE
  • TIME

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