Template-controlled synthesis of chiral cyclohexylhemicucurbit[8]uril

E. Prigorchenko, M. Öeren, S. Kaabel, M. Fomitšenko, I. Reile, I. Järving, T. Tamm, F. Topić, K. Rissanen, R. Aav*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

31 Citations (Scopus)


Enantiomerically pure cyclohexylhemicucurbit[8]uril (cycHC[8]), possessing a barrel-shaped cavity, has been prepared in high yield on a gram scale from either (R,R,N,N′)-cyclohex-1,2-diylurea and formaldehyde or cycHC[6]. In either case, a dynamic covalent library is first generated from which the desired cycHC can be amplified using a suitable anion template.

Original languageEnglish
Pages (from-to)10921-10924
Number of pages4
JournalChemical Communications
Issue number54
Publication statusPublished - 11 Jul 2015
MoE publication typeA1 Journal article-refereed


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