Synthesis of Chiral Triazole-Based Halogen Bond Donors

Mikk Kaasik, Sandra Kaabel, Kadri Kriis, Ivar Järving, Tõnis Kanger*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

16 Citations (Scopus)

Abstract

The number of applications that use halogen bonding in the fields of self-assembly, supramolecular aggregation, and catalysis is growing. However, the accessibility of chiral halotriazoles shows that there is still a lot more to explore. The simple click-chemistry is applied for the straightforward synthesis of enantiomerically pure mono- and bidentate as well as multifunctional iodotriazole-based XB donors. The methodology is characterized by a wide variability due to easy access of chiral azides.

Original languageEnglish
Pages (from-to)2128-2135
Number of pages8
JournalSynthesis (Germany)
Volume51
Issue number10
DOIs
Publication statusPublished - 2019
MoE publication typeA1 Journal article-refereed

Keywords

  • chiral compounds
  • click chemistry
  • halogen bonds
  • hydrogen bonds
  • nitrogen heterocycles

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