Synthesis of Chiral Triazole-Based Halogen Bond Donors

Mikk Kaasik; Sandra Kaabel; Kadri Kriis; Ivar Järving; Tõnis Kanger

doi:10.1055/s-0037-1610864

Synthesis of Chiral Triazole-Based Halogen Bond Donors

Mikk Kaasik, Sandra Kaabel, Kadri Kriis, Ivar Järving, Tõnis Kanger^*

^*Corresponding author for this work

Not published at Aalto University

Research output: Contribution to journal › Article › Scientific › peer-review

16 Citations (Scopus)

Abstract

The number of applications that use halogen bonding in the fields of self-assembly, supramolecular aggregation, and catalysis is growing. However, the accessibility of chiral halotriazoles shows that there is still a lot more to explore. The simple click-chemistry is applied for the straightforward synthesis of enantiomerically pure mono- and bidentate as well as multifunctional iodotriazole-based XB donors. The methodology is characterized by a wide variability due to easy access of chiral azides.

Original language	English
Pages (from-to)	2128-2135
Number of pages	8
Journal	Synthesis (Germany)
Volume	51
Issue number	10
DOIs	https://doi.org/10.1055/s-0037-1610864
Publication status	Published - 2019
MoE publication type	A1 Journal article-refereed

Keywords

chiral compounds
click chemistry
halogen bonds
hydrogen bonds
nitrogen heterocycles

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AU - Kaasik, Mikk

AU - Kaabel, Sandra

AU - Kriis, Kadri

AU - Järving, Ivar

AU - Kanger, Tõnis

N1 - Publisher Copyright: © Georg Thieme Verlag Stuttgart New York.

PY - 2019

Y1 - 2019

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KW - chiral compounds

KW - click chemistry

KW - halogen bonds

KW - hydrogen bonds

KW - nitrogen heterocycles

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Synthesis of Chiral Triazole-Based Halogen Bond Donors

Abstract

Keywords

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