Switchable asymmetric bio-epoxidation of α,β-unsaturated ketones

Research output: Contribution to journalArticle

Researchers

Research units

  • CAS - Chengdu Institute of Biology

Abstract

Efficient asymmetric bio-epoxidation of electron-deficient α,β-unsaturated ketones was realized via a tandem reduction-epoxidation-dehydrogenation cascade, which proceeds in a switchable manner to afford either chiral epoxy ketones or allylic epoxy alcohols with up to >99% yield and >99%ee.

Details

Original languageEnglish
Pages (from-to)1158-1161
Number of pages4
JournalChemical Communications
Volume52
Issue number6
Publication statusPublished - 2016
MoE publication typeA1 Journal article-refereed

ID: 14582288