TY - JOUR
T1 - Supercritical carbon dioxide extraction of astaxanthin from Paracoccus NBRC 101723
T2 - Mathematical modelling study
AU - Chougle, Jyoti
AU - Bankar, Sandip
AU - Chavan, Prakash
AU - Patravale, Vandana
AU - Singhal, Rekha S.
PY - 2016/9/1
Y1 - 2016/9/1
N2 - Astaxanthin AX is a secondary metabolite that accumulates inside the cell during the Paracoccus fermentation.The fermentation biomass was extracted using supercritical carbon dioxide(SC-CO2).The solubility parameter of AX, CO2, and entrainer solvents was calculated and validated with experimental results.The pressure and particle size of the biomass had a significant effect on the extraction of AX.A maximum recovery of 963.33 μg/g of AXwas obtained after SC-CO2 extraction at 40ºC,350 bar and a run time of 60 min with ethanol (20% v/w) as an entrainer. Further, the experimental data has been modelled using non-linear regression analysis method.
AB - Astaxanthin AX is a secondary metabolite that accumulates inside the cell during the Paracoccus fermentation.The fermentation biomass was extracted using supercritical carbon dioxide(SC-CO2).The solubility parameter of AX, CO2, and entrainer solvents was calculated and validated with experimental results.The pressure and particle size of the biomass had a significant effect on the extraction of AX.A maximum recovery of 963.33 μg/g of AXwas obtained after SC-CO2 extraction at 40ºC,350 bar and a run time of 60 min with ethanol (20% v/w) as an entrainer. Further, the experimental data has been modelled using non-linear regression analysis method.
UR - http://www.scopus.com/inward/record.url?scp=84975144863&partnerID=8YFLogxK
U2 - 10.1080/01496395.2016.1178288
DO - 10.1080/01496395.2016.1178288
M3 - Article
AN - SCOPUS:84975144863
VL - 51
SP - 2164
EP - 2173
JO - Separation Science and Technology
JF - Separation Science and Technology
SN - 0149-6395
IS - 13
ER -