Supercritical carbon dioxide extraction of astaxanthin from Paracoccus NBRC 101723: Mathematical modelling study

Jyoti Chougle, Sandip Bankar, Prakash Chavan, Vandana Patravale, Rekha S. Singhal*

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

1 Citation (Scopus)

Abstract

Astaxanthin AX is a secondary metabolite that accumulates inside the cell during the Paracoccus fermentation.The fermentation biomass was extracted using supercritical carbon dioxide(SC-CO2).The solubility parameter of AX, CO2, and entrainer solvents was calculated and validated with experimental results.The pressure and particle size of the biomass had a significant effect on the extraction of AX.A maximum recovery of 963.33 μg/g of AXwas obtained after SC-CO2 extraction at 40ºC,350 bar and a run time of 60 min with ethanol (20% v/w) as an entrainer. Further, the experimental data has been modelled using non-linear regression analysis method.
Original languageEnglish
Pages (from-to)2164-2173
Number of pages10
JournalSeparation Science and Technology
Volume51
Issue number13
Early online date2016
DOIs
Publication statusPublished - 1 Sep 2016
MoE publication typeA1 Journal article-refereed

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