Stochastic boundary molecular dynamics simulation of l-ribose in the active site of Actinoplanes missouriensis xylose isomerase and its Val135Asn mutant with improved reaction rate

Harri Santa, Juha Kammonen, Olli Lehtonen, Johanna Karimäki, Ossi Pastinen, Matti Leisola, Ossi Turunen

Research output: Contribution to journalArticleScientificpeer-review

15 Citations (Scopus)
Original languageEnglish
Pages (from-to)65-73
JournalBIOCHIMICA ET BIOPHYSICA ACTA: PROTEINS AND PROTEOMICS
Volume1749
Issue number1
Publication statusPublished - 2005
MoE publication typeA1 Journal article-refereed

Keywords

  • catalytic efficiency
  • L-ribose
  • molecular dynamics
  • site-directed mutagenesis
  • xylose isomerase

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