Spatio-temporal profile of brain activity during gentle touch investigated with magnetoencephalography

Research output: Contribution to journalArticle

Standard

Spatio-temporal profile of brain activity during gentle touch investigated with magnetoencephalography. / Eriksson Hagberg, Elin; Ackerley, Rochelle; Lundqvist, Daniel; Schneiderman, Justin; Jousmäki, Veikko; Wessberg, J.

In: NeuroImage, Vol. 201, 116024, 01.11.2019.

Research output: Contribution to journalArticle

Harvard

APA

Vancouver

Author

Eriksson Hagberg, Elin ; Ackerley, Rochelle ; Lundqvist, Daniel ; Schneiderman, Justin ; Jousmäki, Veikko ; Wessberg, J. / Spatio-temporal profile of brain activity during gentle touch investigated with magnetoencephalography. In: NeuroImage. 2019 ; Vol. 201.

Bibtex - Download

@article{a69e6c4cc9d8452d88804c1e68625cda,
title = "Spatio-temporal profile of brain activity during gentle touch investigated with magnetoencephalography",
abstract = "Positive affective touch plays a central role in social and inter-personal interactions. Low-threshold mechanoreceptive afferents, including slowly-conducting C-tactile (CT) afferents found in hairy skin, transmit such signals from gentle touch to the brain. Tactile signals are processed, in part, by the posterior insula, where it is the thought to be the primary target for CTs. We used magnetoencephalography (MEG) to assess brain activity evoked by gentle, naturalistic stroking touch on the arm delivered by a new MEG-compatible brush robot. We aimed to use high temporal resolution MEG to allow us to distinguish between brain responses from fast-conducting Aβ and slowly-conducting CT afferents. Brush strokes were delivered to the left upper arm and left forearm of 15 healthy participants. We hypothesized that late brain responses, due to slow CT afference, would appear with a time shift between the two different locations on the arm. Our results show that gentle touch rapidly activated somatosensory, motor, and cingulate regions within the first 100 ms of skin contact, which was driven by fast-conducting mechanoreceptive afference, and that these responses were sustained during touch. Peak latencies in the posterior insula were shifted as a function of stimulus location and temporally-separate posterior insula activations were induced by Aβ and CT afference that may modulate the emotional processing of gentle touch on hairy skin. We conclude that the detailed information regarding temporal and spatial brain activity from MEG provides new insights into the central processing of gentle, naturalistic touch, which is thought to underpin affective tactile interactions.",
keywords = "C-Tactile, MEG, Pleasant, Somatosensory, Stroking, Touch",
author = "{Eriksson Hagberg}, Elin and Rochelle Ackerley and Daniel Lundqvist and Justin Schneiderman and Veikko Jousm{\"a}ki and J. Wessberg",
year = "2019",
month = "11",
day = "1",
doi = "10.1016/j.neuroimage.2019.116024",
language = "English",
volume = "201",
journal = "NeuroImage",
issn = "1053-8119",

}

RIS - Download

TY - JOUR

T1 - Spatio-temporal profile of brain activity during gentle touch investigated with magnetoencephalography

AU - Eriksson Hagberg, Elin

AU - Ackerley, Rochelle

AU - Lundqvist, Daniel

AU - Schneiderman, Justin

AU - Jousmäki, Veikko

AU - Wessberg, J.

PY - 2019/11/1

Y1 - 2019/11/1

N2 - Positive affective touch plays a central role in social and inter-personal interactions. Low-threshold mechanoreceptive afferents, including slowly-conducting C-tactile (CT) afferents found in hairy skin, transmit such signals from gentle touch to the brain. Tactile signals are processed, in part, by the posterior insula, where it is the thought to be the primary target for CTs. We used magnetoencephalography (MEG) to assess brain activity evoked by gentle, naturalistic stroking touch on the arm delivered by a new MEG-compatible brush robot. We aimed to use high temporal resolution MEG to allow us to distinguish between brain responses from fast-conducting Aβ and slowly-conducting CT afferents. Brush strokes were delivered to the left upper arm and left forearm of 15 healthy participants. We hypothesized that late brain responses, due to slow CT afference, would appear with a time shift between the two different locations on the arm. Our results show that gentle touch rapidly activated somatosensory, motor, and cingulate regions within the first 100 ms of skin contact, which was driven by fast-conducting mechanoreceptive afference, and that these responses were sustained during touch. Peak latencies in the posterior insula were shifted as a function of stimulus location and temporally-separate posterior insula activations were induced by Aβ and CT afference that may modulate the emotional processing of gentle touch on hairy skin. We conclude that the detailed information regarding temporal and spatial brain activity from MEG provides new insights into the central processing of gentle, naturalistic touch, which is thought to underpin affective tactile interactions.

AB - Positive affective touch plays a central role in social and inter-personal interactions. Low-threshold mechanoreceptive afferents, including slowly-conducting C-tactile (CT) afferents found in hairy skin, transmit such signals from gentle touch to the brain. Tactile signals are processed, in part, by the posterior insula, where it is the thought to be the primary target for CTs. We used magnetoencephalography (MEG) to assess brain activity evoked by gentle, naturalistic stroking touch on the arm delivered by a new MEG-compatible brush robot. We aimed to use high temporal resolution MEG to allow us to distinguish between brain responses from fast-conducting Aβ and slowly-conducting CT afferents. Brush strokes were delivered to the left upper arm and left forearm of 15 healthy participants. We hypothesized that late brain responses, due to slow CT afference, would appear with a time shift between the two different locations on the arm. Our results show that gentle touch rapidly activated somatosensory, motor, and cingulate regions within the first 100 ms of skin contact, which was driven by fast-conducting mechanoreceptive afference, and that these responses were sustained during touch. Peak latencies in the posterior insula were shifted as a function of stimulus location and temporally-separate posterior insula activations were induced by Aβ and CT afference that may modulate the emotional processing of gentle touch on hairy skin. We conclude that the detailed information regarding temporal and spatial brain activity from MEG provides new insights into the central processing of gentle, naturalistic touch, which is thought to underpin affective tactile interactions.

KW - C-Tactile

KW - MEG

KW - Pleasant

KW - Somatosensory

KW - Stroking

KW - Touch

UR - http://www.scopus.com/inward/record.url?scp=85069851272&partnerID=8YFLogxK

U2 - 10.1016/j.neuroimage.2019.116024

DO - 10.1016/j.neuroimage.2019.116024

M3 - Article

VL - 201

JO - NeuroImage

JF - NeuroImage

SN - 1053-8119

M1 - 116024

ER -

ID: 36027788