Self-assembly of ultra-small micelles from amphiphilic lipopeptoids

Research output: Contribution to journalArticle

Researchers

  • King Hang Aaron Lau
  • Valeria Castelletto
  • Thomas Kendall
  • Jan Sefcik
  • Ian W. Hamley
  • Mehedi Reza
  • Janne Ruokolainen

Research units

  • University of Strathclyde
  • University of Reading

Abstract

Poly(N-substituted glycine) “peptoids” constitute a promising class of peptide-mimetic materials. We introduce the self-assembly of lipopeptoids into spherical micelles ca. 5 nm in diameter as well as larger assemblies by varying the peptoid sequence design. Our results point to design rules for the self-assembly of peptoid nanostructures, enabling the creation of stable, ultra-small peptidomimetic nanospheres.

Details

Original languageEnglish
Pages (from-to)2178-2181
Number of pages4
JournalChemical Communications
Volume53
Issue number13
Publication statusPublished - 2017
MoE publication typeA1 Journal article-refereed

ID: 10995857