Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic

Dominic van der Waals, Leo E. Heim, Simona Vallazza, Christian Gedig, Jan Deska, Martin H. G. Prechtl

Research output: Contribution to journalArticleScientificpeer-review

13 Citations (Scopus)
123 Downloads (Pure)


The catalytic networks of methylotrophic organisms, featuring redox enzymes for the activation of one-carbon moieties, can serve as great inspiration in the development of novel homogeneously catalyzed pathways for the interconversion of C1 molecules at ambient conditions. An imidazolium-tagged arene–ruthenium complex was identified as an effective functional mimic of the bacterial formaldehyde dismutase, which provides a new and highly selective route for the conversion of formaldehyde to methanol in absence of any external reducing agents. Moreover, secondary amines are reductively methylated by the organometallic dismutase mimic in a redox self-sufficient manner with formaldehyde acting both as carbon source and reducing agent.
Original languageEnglish
Pages (from-to)11568-11573
Number of pages6
Issue number33
Publication statusPublished - 6 Jul 2016
MoE publication typeA1 Journal article-refereed


  • biocatalysis
  • ionic liquid
  • methanol
  • reductive methylation
  • Ruthenium


Dive into the research topics of 'Self-Sufficient Formaldehyde-to-Methanol Conversion by Organometallic Formaldehyde Dismutase Mimic'. Together they form a unique fingerprint.

Cite this