Selective detection of morphine in the presence of paracetamol with anodically pretreated dual layer Ti/tetrahedral amorphous carbon electrodes

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@article{a9e256fdf0d64d629ae53a7dc6f3b6d6,
title = "Selective detection of morphine in the presence of paracetamol with anodically pretreated dual layer Ti/tetrahedral amorphous carbon electrodes",
abstract = "We investigated the effect of anodic treatment of titanium/tetrahedral amorphous carbon electrodes on the electrochemical detection of morphine and paracetamol. The anodic treatment caused both oxidation of the carbon and, more importantly, exposure and oxidation of the underlying Ti layer. This treatment anodically shifted the oxidation potential of paracetamol while that of morphine remained unaffected. The resulting electrode also showed better selectivity than a ta-C electrode without Ti. After anodic treatment at 2.5 V, selective detection of morphine with a physiologically meaningful detection limit of 9.8 nM and a linear range of 0.1–10 μM was obtained in the presence of 100 μM paracetamol.",
keywords = "Morphine, Paracetamol, Tetrahedral amorphous carbon, Titanium, Voltammetry",
author = "Niklas Wester and Jarkko Etula and Tuomas Lilius and Sami Sainio and Tomi Laurila and Jari Koskinen",
year = "2018",
month = "1",
day = "1",
doi = "10.1016/j.elecom.2017.12.014",
language = "English",
volume = "86",
pages = "166--170",
journal = "Electrochemistry Communications",
issn = "1388-2481",

}

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TY - JOUR

T1 - Selective detection of morphine in the presence of paracetamol with anodically pretreated dual layer Ti/tetrahedral amorphous carbon electrodes

AU - Wester, Niklas

AU - Etula, Jarkko

AU - Lilius, Tuomas

AU - Sainio, Sami

AU - Laurila, Tomi

AU - Koskinen, Jari

PY - 2018/1/1

Y1 - 2018/1/1

N2 - We investigated the effect of anodic treatment of titanium/tetrahedral amorphous carbon electrodes on the electrochemical detection of morphine and paracetamol. The anodic treatment caused both oxidation of the carbon and, more importantly, exposure and oxidation of the underlying Ti layer. This treatment anodically shifted the oxidation potential of paracetamol while that of morphine remained unaffected. The resulting electrode also showed better selectivity than a ta-C electrode without Ti. After anodic treatment at 2.5 V, selective detection of morphine with a physiologically meaningful detection limit of 9.8 nM and a linear range of 0.1–10 μM was obtained in the presence of 100 μM paracetamol.

AB - We investigated the effect of anodic treatment of titanium/tetrahedral amorphous carbon electrodes on the electrochemical detection of morphine and paracetamol. The anodic treatment caused both oxidation of the carbon and, more importantly, exposure and oxidation of the underlying Ti layer. This treatment anodically shifted the oxidation potential of paracetamol while that of morphine remained unaffected. The resulting electrode also showed better selectivity than a ta-C electrode without Ti. After anodic treatment at 2.5 V, selective detection of morphine with a physiologically meaningful detection limit of 9.8 nM and a linear range of 0.1–10 μM was obtained in the presence of 100 μM paracetamol.

KW - Morphine

KW - Paracetamol

KW - Tetrahedral amorphous carbon

KW - Titanium

KW - Voltammetry

UR - http://www.scopus.com/inward/record.url?scp=85038095172&partnerID=8YFLogxK

U2 - 10.1016/j.elecom.2017.12.014

DO - 10.1016/j.elecom.2017.12.014

M3 - Article

VL - 86

SP - 166

EP - 170

JO - Electrochemistry Communications

JF - Electrochemistry Communications

SN - 1388-2481

ER -

ID: 16586452