Scalable synthesis of (-)-trans-3-hydroxypipecolic acid via a useful chiral building block

Oskari K. Karjalainen, Ari M.P. Koskinen

    Research output: Contribution to journalArticleScientificpeer-review

    9 Citations (Scopus)
    145 Downloads (Pure)

    Abstract

    A scalable synthesis of ()-trans-2-(hydroxymethyl)-1,2,3,6-tetrahydropyridin-
    3-ol, a versatile chiral building block is described along with its transformation
    to ()-trans-3-hydroxypipecolic acid.
    Original languageEnglish
    Pages (from-to)2444-2448
    JournalTetrahedron
    Volume70
    Issue number14
    DOIs
    Publication statusPublished - 2014
    MoE publication typeA1 Journal article-refereed

    Keywords

    • amino alcohol
    • diastereoselective synthesis
    • hydroxypipecolic acid

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