Protein-dendron conjugates for DNA binding: understanding the effect of the protein core on multivalency

Giovanni M. Pavan*, Mauri A. Kostiainen, Andrea Danani

*Corresponding author for this work

Research output: Contribution to journalArticleScientificpeer-review

7 Citations (Scopus)

Abstract

In this work we have used molecular dynamics simulations to explore the binding between two different protein-dendron conjugates and double stranded DNA. Different protein cores protect the binding site from the external environment, but can also influence the multivalent recognition between the spermine ligands of the dendron and the DNA.

Original languageEnglish
Pages (from-to)1677-1681
Number of pages5
JournalRSC Advances
Volume1
Issue number9
DOIs
Publication statusPublished - 24 Oct 2011
MoE publication typeA1 Journal article-refereed

Keywords

  • DENDRIMERS
  • MOLECULES
  • ADHESION
  • SIRNA

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