Abstract
Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.
Original language | English |
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Patent number | US2015176044 |
IPC | C12N 15/ 80 A I |
Priority date | 23/05/2013 |
Publication status | Published - 25 Jun 2015 |
MoE publication type | H1 Granted patent |
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Jukka Seppälä (Manager)
School of Chemical EngineeringFacility/equipment: Facility