Production of Fucosylated Glycoproteins

JARI NATUNEN; ANN WESTERHOLM-PARVINEN; HANNA SALO; JUSSI JOENSUU; HELI VISKARI; CHRISTOPHER LANDOWSKI; ANNE HUUSKONEN; ANNE KANERVA; ANNA-LIISA HANNINEN; NOORA SALOVUORI; Merja Penttilä; JUHANI SAARINEN; MARKKU SALOHEIMO

Production of Fucosylated Glycoproteins

JARI NATUNEN (Inventor), ANN WESTERHOLM-PARVINEN (Inventor), HANNA SALO (Inventor), JUSSI JOENSUU (Inventor), HELI VISKARI (Inventor), CHRISTOPHER LANDOWSKI (Inventor), ANNE HUUSKONEN (Inventor), ANNE KANERVA (Inventor), ANNA-LIISA HANNINEN (Inventor), NOORA SALOVUORI (Inventor), Merja Penttilä (Inventor), JUHANI SAARINEN (Inventor), MARKKU SALOHEIMO (Inventor)

Department of Bioproducts and Biosystems

Research output: Patent

Abstract

Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.

Original language	English
Patent number	US2015176044
IPC	C12N 15/ 80 A I
Priority date	23/05/2013
Publication status	Published - 25 Jun 2015
MoE publication type	H1 Granted patent

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title = "Production of Fucosylated Glycoproteins",

abstract = "Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.",

author = "JARI NATUNEN and ANN WESTERHOLM-PARVINEN and HANNA SALO and JUSSI JOENSUU and HELI VISKARI and CHRISTOPHER LANDOWSKI and ANNE HUUSKONEN and ANNE KANERVA and ANNA-LIISA HANNINEN and NOORA SALOVUORI and Merja Penttil{\"a} and JUHANI SAARINEN and MARKKU SALOHEIMO",

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TY - PAT

T1 - Production of Fucosylated Glycoproteins

AU - NATUNEN, JARI

AU - WESTERHOLM-PARVINEN, ANN

AU - SALO, HANNA

AU - JOENSUU, JUSSI

AU - VISKARI, HELI

AU - LANDOWSKI, CHRISTOPHER

AU - HUUSKONEN, ANNE

AU - KANERVA, ANNE

AU - HANNINEN, ANNA-LIISA

AU - SALOVUORI, NOORA

AU - Penttilä, Merja

AU - SAARINEN, JUHANI

AU - SALOHEIMO, MARKKU

PY - 2015/6/25

Y1 - 2015/6/25

N2 - Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.

AB - Described herein are compositions including filamentous fungal cells, such as Trichoderma fungal cells, having reduced protease activity and expressing fucosylation pathway. Further described herein are methods for producing a glycoprotein having fucosylated N-glycan, using genetically modified filamentous fungal cells, for example, Trichoderma fungal cells, as the expression system.

M3 - Patent

M1 - US2015176044

ER -

Production of Fucosylated Glycoproteins

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