Process for modifying glucose repression

MARJA ILMÉN (Inventor), HANS SOEDERLUND (Inventor), MERJA PENTTILÄ (Inventor)

Research output: Patent

Abstract

The present invention relates to recombinant-DNA-technology, and particularly to genes involved in the control of basic metabolic processes in fungi. The invention specifically provides a mutated form of the native glucose repressor gene cre of filamentous fungi, wherein the mutation is situated in the C-terminal domain, the N-terminal first zinc finger being intact and the C-terminal region including the second zinc finger being mutated so that the viability of a strain carrying said mutated gene is maintained and the glucose repression is relieved.

Original languageEnglish
Patent numberUS6326477
IPCC12R 1/ 885 A N
Priority date30/08/1996
Publication statusPublished - 4 Dec 2001
MoE publication typeH1 Granted patent

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