Preliminary results of non-contact THz imaging of cornea

Shijun Sung, James Garritano, Neha Bajwa, Sophie Deng, Jean Pierre Hubschman, Warren S. Grundfest, Zachary D. Taylor*

*Corresponding author for this work

Research output: Contribution to journalConference articleScientificpeer-review

12 Citations (Scopus)
53 Downloads (Pure)

Abstract

This paper presents a novel THz optical design that allows the acquisition of THz reflectivity maps of in vivo cornea without the need for a field flattening window and preliminary imaging results of in vivo rabbit cornea. The system's intended use is to sense small changes in corneal tissue water content (CTWC) that can be precursors for a host of diseases and pathologies. Unique beam optics allows the scanning of a curved surface at normal incidence while keeping the source detector and target stationary. Basic system design principles are discussed and image sets of spherical calibration targets and corneal phantom models are presented. The presented design will enable, for the first time, non-contact THz imaging of animal and human cornea.

Original languageEnglish
Article number93620C
JournalProceedings of SPIE - The International Society for Optical Engineering
Volume9362
Issue numberJanuary
DOIs
Publication statusPublished - 1 Jan 2015
MoE publication typeA4 Article in a conference publication

Keywords

  • Optical design
  • Quasioptics
  • THz medical imaging

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