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Abstract
We use a combination of computer simulations and isoflux tension propagation (IFTP) theory to investigate the translocation dynamics of a flexible linear polymer through a nanopore into an environment composed of repulsive active rods in two dimensions. We demonstrate that the rod activity induces a crowding effect on the polymer, leading to a time-dependent effective net force that facilitates translocation into the active environment. Incorporating this force into the IFTP theory for pore-driven translocation allows us to characterize translocation dynamics in detail and derive a scaling form for the average translocation time as τ ∼ N1+v01 Lvt/FSP, where N01, Lr, and FSP are the initial contour length of the cis-side subchain, rod length, and self-propelling force acting on the rods, respectively, and ν is the equilibrium Flory scaling exponent.
Original language | English |
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Article number | 013080 |
Number of pages | 7 |
Journal | PHYSICAL REVIEW RESEARCH |
Volume | 3 |
Issue number | 1 |
DOIs | |
Publication status | Published - 26 Jan 2021 |
MoE publication type | A1 Journal article-refereed |
Keywords
- DNA
- FORCE
- TRANSITION
- ROTATION
- SWIMMER
- MOTION
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Dive into the research topics of 'Polymer translocation through a nanopore assisted by an environment of active rods'. Together they form a unique fingerprint.Projects
- 1 Finished
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PolyDyna: Coarse-Grained Modeling of Translocation and Polymer Dynamics in Nanofluidic Systems
Ala-Nissilä, T., Achim, C., Alipour, S., Alcanzare, M., Muhli, H., Seyedheydari, F., Molla, J., Hirvonen, P., Babu, A., Hashemi Petrudi, A., Vadimov, V., Ferreira Sampaio, R., Conley, K. & Fan, Z.
01/09/2017 → 31/12/2021
Project: Academy of Finland: Other research funding