pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface

Sulan Colak; Paulina Guzman; Natalie Medlicott; Heikki Tenhu; Jukka Niskanen; Anu Alhoranta; Lene Jorgensen; Stefania Baldursdottir

pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface

Sulan Colak
, Paulina Guzman
, Natalie Medlicott
, Heikki Tenhu
, Jukka Niskanen
, Anu Alhoranta
, Lene Jorgensen
, Stefania Baldursdottir^*

^*Corresponding author for this work

Not published at Aalto University

Research output: Contribution to journal › Conference article › Scientific › peer-review

Abstract

Bovine serum albumin (BSA) adsorption to oil-water interfaces was studied in the presence and absence of two linear polymers poly(dimethylamino)ethyl methacrylate (PDMAEMA) and PDMAEMA-block-[poly butyl acetate]₃₈₇₀₀-PDMAEMA₃₃₀₀₀ (PBuA). As the hydrophobicity of the polymers is pH dependent, the pH was varied using pH 6.6, 7.0 and 7.4 during the measurements. Pendant drop and a rheometer with double wall ring geometry were utilized for surface tension and oscillatory shear measurements, respectively. The presence of both the PDMAEME and the PBuA resulted in decreased adsorption of BSA with increasing pH where PBuA was more efficient. The greatest reduction of the interfacial complex viscosity was reached in the presence of PBuA at pH 7.4.

Original language	English
Pages (from-to)	329–334
Journal	Annual Transactions of the Nordic Rheology Society
Volume	21
Publication status	Published - 2013
MoE publication type	A4 Conference publication

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title = "pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface",

abstract = "Bovine serum albumin (BSA) adsorption to oil-water interfaces was studied in the presence and absence of two linear polymers poly(dimethylamino)ethyl methacrylate (PDMAEMA) and PDMAEMA-block-[poly butyl acetate]38700-PDMAEMA33000 (PBuA). As the hydrophobicity of the polymers is pH dependent, the pH was varied using pH 6.6, 7.0 and 7.4 during the measurements. Pendant drop and a rheometer with double wall ring geometry were utilized for surface tension and oscillatory shear measurements, respectively. The presence of both the PDMAEME and the PBuA resulted in decreased adsorption of BSA with increasing pH where PBuA was more efficient. The greatest reduction of the interfacial complex viscosity was reached in the presence of PBuA at pH 7.4.",

author = "Sulan Colak and Paulina Guzman and Natalie Medlicott and Heikki Tenhu and Jukka Niskanen and Anu Alhoranta and Lene Jorgensen and Stefania Baldursdottir",

year = "2013",

language = "English",

volume = "21",

pages = "329–334",

journal = "Annual Transactions of the Nordic Rheology Society",

issn = "1601-4057",

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TY - JOUR

T1 - pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface

AU - Colak, Sulan

AU - Guzman, Paulina

AU - Medlicott, Natalie

AU - Tenhu, Heikki

AU - Niskanen, Jukka

AU - Alhoranta, Anu

AU - Jorgensen, Lene

AU - Baldursdottir, Stefania

PY - 2013

Y1 - 2013

N2 - Bovine serum albumin (BSA) adsorption to oil-water interfaces was studied in the presence and absence of two linear polymers poly(dimethylamino)ethyl methacrylate (PDMAEMA) and PDMAEMA-block-[poly butyl acetate]38700-PDMAEMA33000 (PBuA). As the hydrophobicity of the polymers is pH dependent, the pH was varied using pH 6.6, 7.0 and 7.4 during the measurements. Pendant drop and a rheometer with double wall ring geometry were utilized for surface tension and oscillatory shear measurements, respectively. The presence of both the PDMAEME and the PBuA resulted in decreased adsorption of BSA with increasing pH where PBuA was more efficient. The greatest reduction of the interfacial complex viscosity was reached in the presence of PBuA at pH 7.4.

AB - Bovine serum albumin (BSA) adsorption to oil-water interfaces was studied in the presence and absence of two linear polymers poly(dimethylamino)ethyl methacrylate (PDMAEMA) and PDMAEMA-block-[poly butyl acetate]38700-PDMAEMA33000 (PBuA). As the hydrophobicity of the polymers is pH dependent, the pH was varied using pH 6.6, 7.0 and 7.4 during the measurements. Pendant drop and a rheometer with double wall ring geometry were utilized for surface tension and oscillatory shear measurements, respectively. The presence of both the PDMAEME and the PBuA resulted in decreased adsorption of BSA with increasing pH where PBuA was more efficient. The greatest reduction of the interfacial complex viscosity was reached in the presence of PBuA at pH 7.4.

UR - https://nordicrheologysociety.org/AnnualTransactions/ShowAllTransactions?selectedYear=2013

M3 - Conference article

SN - 1601-4057

VL - 21

SP - 329

EP - 334

JO - Annual Transactions of the Nordic Rheology Society

JF - Annual Transactions of the Nordic Rheology Society

ER -

pH dependent polymer surfactants for hindering BSA adsorption to oil-water interface

Abstract

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