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Abstract
The inflammatory-associated corrosion of metallic dental and orthopedic implants causes significant complications, which may result in the implant’s failure. The corrosion resistance can be improved with coatings and surface treatments, but at the same time, it might affect the ability of metallic implants to undergo proper osteointegration. In this work, alginate hydrogels with and without octacalcium phosphate (OCP) were made on 3D-printed (patterned) titanium alloys (Ti Group 2 and Ti-Al-V Group 23) to enhance their anticorrosion properties in simulated normal, inflammatory, and severe inflammatory conditions in vitro. Alginate (Alg) and OCP-laden alginate (Alg/OCP) hydrogels were manufactured on the surface of 3D-printed Ti substrates and were characterized with wettability analysis, XRD, and FTIR. The electrochemical characterization of the samples was carried out with open circuit potential, potentiodynamic polarization, and electrochemical impedance spectroscopy (EIS). It was observed that the hydrophilicity of Alg/OCP coatings was higher than that of pure Alg and that OCP phase crystallinity was increased when samples were subjected to simulated biological media. The corrosion resistance of uncoated and coated samples was lower in inflammatory and severe inflammatory environments vs. normal media, but the hydrogel coatings on 3D-printed Ti layers moved the corrosion potential towards more nobler values, reducing the corrosion current density in all simulated solutions. These measurements revealed that OCP particles in the Alg hydrogel matrix noticeably increased the electrical charge transfer resistance at the substrate and coating interface more than with Alg hydrogel alone.
Original language | English |
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Article number | 13135 |
Number of pages | 16 |
Journal | International Journal of Molecular Sciences |
Volume | 24 |
Issue number | 17 |
DOIs | |
Publication status | Published - 24 Aug 2023 |
MoE publication type | A1 Journal article-refereed |
Keywords
- alginate
- electrochemical behavior
- hydrogel
- implants
- octacalcium phosphate
- simulated inflammatory conditions
- titanium
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Dive into the research topics of 'Octacalcium Phosphate-Laden Hydrogels on 3D-Printed Titanium Biomaterials Improve Corrosion Resistance in Simulated Biological Media'. Together they form a unique fingerprint.Projects
- 1 Finished
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PREMUROSA: Precision medicine for muscoloskeletal regeneration, prosthetics and active ageing
Gasik, M. (Principal investigator) & Bordbar Khiabani, A. (Project Member)
01/01/2020 → 30/09/2024
Project: EU: MC
Press/Media
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Researcher from Aalto University Foundation Reports Recent Findings in Anions (Octacalcium Phosphate-Laden Hydrogels on 3D-Printed Titanium Biomaterials Improve Corrosion Resistance in Simulated Biological Media)
Gasik, M. & Bordbar Khiabani, A.
13/09/2023
1 item of Media coverage
Press/Media: Media appearance