Novel brewing yeast hybrids: creation and application

Research output: Contribution to journalLiterature review

Researchers

  • Kristoffer Krogerus
  • Frederico Magalhaes
  • Virve Vidgren
  • Brian Gibson

Research units

  • VTT Technical Research Centre of Finland

Abstract

The natural interspecies Saccharomyces cerevisiae x Saccharomyces eubayanus hybrid yeast is responsible for global lager beer production and is one of the most important industrial microorganisms. Its success in the lager brewing environment is due to a combination of traits not commonly found in pure yeast species, principally low-temperature tolerance, and maltotriose utilization. Parental transgression is typical of hybrid organisms and has been exploited previously for, e.g., the production of wine yeast with beneficial properties. The parental strain S. eubayanus has only been discovered recently and newly created lager yeast strains have not yet been applied industrially. A number of reports attest to the feasibility of this approach and artificially created hybrids are likely to have a significant impact on the future of lager brewing. De novo S. cerevisiae x S. eubayanus hybrids outperform their parent strains in a number of respects, including, but not restricted to, fermentation rate, sugar utilization, stress tolerance, and aroma formation. Hybrid genome function and stability, as well as different techniques for generating hybrids and their relative merits are discussed. Hybridization not only offers the possibility of generating novel non-GM brewing yeast strains with unique properties, but is expected to aid in unraveling the complex evolutionary history of industrial lager yeast.

Details

Original languageEnglish
Pages (from-to)65-78
Number of pages14
JournalApplied Microbiology and Biotechnology
Volume101
Issue number1
Publication statusPublished - Jan 2017
MoE publication typeA1 Journal article-refereed

    Research areas

  • Lager, S. eubayanus, Brewing, Mating, Heterosis, Aroma, Stress tolerance, Stability, BOTTOM-FERMENTING YEAST, BAYANUS VAR. UVARUM, SACCHAROMYCES INTERSPECIFIC HYBRIDS, IMPROVED FERMENTATION PERFORMANCE, SENSU-STRICTO COMPLEX, HIGH SSU1 EXPRESSION, LAGER YEAST, BREWERS-YEAST, NATURAL HYBRIDS, LOW-TEMPERATURE

ID: 10728344