Mild Traumatic Brain Injury Affects Cognitive Processing and Modifies Oscillatory Brain Activity during Attentional Tasks

Research output: Contribution to journalArticleScientificpeer-review

Researchers

Research units

  • MEGIN Elekta Oy
  • Lohja District Hospital
  • University of Helsinki
  • Helsinki University Central Hospital

Abstract

Despite the high prevalence of mild traumatic brain injury (mTBI), current diagnostic tools to objectively assess cognitive complaints after mTBI continue to be inadequate. Our aim was to identify neuronal correlates for cognitive difficulties in mTBI patients by evaluating the possible alterations in oscillatory brain activity during a behavioral task known to be sensitive to cognitive impairment after mTBI. We compared oscillatory brain activity during rest and cognitive tasks (Paced Auditory Serial Addition Test [PASAT] and a vigilance test [VT]) with magnetoencephalography between 25 mTBI patients and 20 healthy controls. Whereas VT induced no significant differences compared with resting state in either group, patients exhibited stronger attenuation of 8- to 14-Hz oscillatory activity during PASAT than healthy controls in the left parietotemporal cortex (p

Details

Original languageEnglish
Number of pages11
JournalJOURNAL OF NEUROTRAUMA
Publication statusE-pub ahead of print - 10 Apr 2019
MoE publication typeA1 Journal article-refereed

    Research areas

  • alpha frequency modulation, cognitive task, magnetoencephalography, mild traumatic brain injury, SERIAL ADDITION TEST, MINOR HEAD-INJURY, TEST-RETEST RELIABILITY, INTRAINDIVIDUAL VARIABILITY, SUSTAINED ATTENTION, ALPHA-ACTIVITY, EEG SPECTRA, MEMORY, LOCALIZATION, PERFORMANCE

ID: 33659667