This invention relates to a method for cultivating yeast in lignocellulosic hydrol- ysate and methods of improving yeast viability and/or metabolic activity when cultivated on medium comprising lignocellulosic hydrolysate or in a culture me- dium comprising lignocellulosic hydrolysate or in other formic and acetic acid containing media. The method comprises that yeast is made deficient of a gene encoding the plasma membrane transporter Pdr12 or its homologue. The in- vention relates also to the yeast culture and modified yeast host. The invention improves production of desired products on lignocellulosic or acidic medium.
|IPC||C12P 7/ 18 A I|
|Publication status||Published - 28 May 2015|
|MoE publication type||H1 Granted patent|